Substance |
Info | Dose |
Warn | Link |
PubMed |
Latest article |
Curcumin | 📋 | ✍ | ⛔ | | 38299401 | Curcumin Inhibits Vasculogenic Mimicry Via Regulating ETS-1 in Renal Cell Carcinoma |
Vitamin D3 | 📋 | ✍ | ⛔ | | 38558206 | Vitamin D inhibits ferroptosis and mitigates the kidney injury of prediabetic mice by activating the Klotho/p53 signaling pathway |
Melatonin | 📋 | ✍ | ⛔ | | 38713551 | Melatonin attenuates renal ischemia-reperfusion injury by regulating mitochondrial dynamics and autophagy through AMPK/DRP1 |
Saw Palmetto | 📋 | ✍ | ⛔ | | 36498751 | The Role of Combination Therapy with α-Blockers and Hexanic Extract of Serenoa repens in the Treatment of LUTS/BPH |
Resveratrol | 📋 | ✍ | ⛔ | | 38529522 | A short treatment with resveratrol after a renal ischaemia-reperfusion injury prevents maladaptive repair and long-term chronic kidney disease in rats |
Astragalosides | 📋 | ✍ | ⛔ | | 38572426 | Astragaloside IV attenuates renal tubule injury in DKD rats via suppression of CD36-mediated NLRP3 inflammasome activation |
Quercetin | 📋 | ✍ | ⛔ | | 38726926 | The nephroprotective effect of Quercetin in Cyclophosphamide-induced renal toxicity might be associated with MAPK/ERK and NF-κB signal modulation activity |
Berberine | 📋 | ✍ | ⛔ | | 38705399 | Berberine alleviated contrast-induced acute kidney injury by mitophagy-mediated NLRP3 inflammasome inactivation in a mice model |
Cranberry | 📋 | ✍ | ⛔ | | 38651941 | Cranberry Polyphenols and Prevention against Urinary Tract Infections: New Findings Related to the Integrity and Functionality of Intestinal and Urinary Barriers |
Astragalus Root | 📋 | ✍ | ⛔ | | 38404557 | The effect of Astragali Radix-Radix Angelica Sinensis on acute kidney injury: a network pharmacology and molecular docking study |
Vitamin C | 📋 | ✍ | ⛔ | | 38721680 | Oral preparation of hyaluronic acid, chondroitin sulfate, N-acetylglucosamine, and vitamin C improves sexual and urinary symptoms in participants with recurrent urinary tract infections: a randomized crossover trial |
Ginsenosides | 📋 | ✍ | ⛔ | | 38683298 | Integrative informatics analysis identifies that ginsenoside Re improves renal fibrosis through regulation of autophagy |
Lycopene | 📋 | ✍ | ⛔ | | 38584465 | Lycopene from tomatoes and tomato products exerts renoprotective effects by ameliorating oxidative stress, apoptosis, pyroptosis, fibrosis, and inflammatory injury in calcium oxalate nephrolithiasis: the underlying mechanisms |
Metformin | 📋 | ✍ | ⛔ | | 38352949 | Metformin: A promising clinical therapeutical approach for BPH treatment via inhibiting dysregulated steroid hormones-induced prostatic epithelial cells proliferation |
Sulforaphane | 📋 | ✍ | ⛔ | | 38474751 | Sulforaphane Inhibits Adhesion and Migration of Cisplatin- and Gemcitabine-Resistant Bladder Cancer Cells In Vitro |
EGCG | 📋 | ✍ | ⛔ | | 38084438 | G3BP1 and SLU7 Jointly Promote Immune Evasion by Downregulating MHC-I via PI3K/Akt Activation in Bladder Cancer |
N-Acetyl Cysteine | 📋 | ✍ | ⛔ | | 38004033 | N-Acetylcysteine Alleviates the Progression of Chronic Kidney Disease: A Three-Year Cohort Study |
Ginseng | 📋 | ✍ | ⛔ | | 38460576 | Red ginseng ameliorates lipotoxicity-induced renal fibrosis in hyperuricemia mice |
Nigella Sativa | 📋 | ✍ | ⛔ | | 37009001 | Comparison of the anti-diabetic and nephroprotective activities of vitamin E, metformin, and Nigella sativa oil on kidney in experimental diabetic rats |
Magnesium | 📋 | ✍ | ⛔ | | 38110607 | Dietary Magnesium Intake and Proteinuria: Is There a Relationship? |
Apigenin | 📋 | ✍ | ⛔ | | 38718656 | Boswellic acid and apigenin alleviate methotrexate-provoked renal and hippocampal alterations in rats: Targeting autophagy, NOD-2/NF-κB/NLRP3, and connexin-43 |
Thymoquinone | 📋 | | ⛔ | | 38715182 | Thymoquinone: An Effective Natural Compound for Kidney Protection |
Grape Seed extract | 📋 | ✍ | ⛔ | | 36686673 | Grape seed proanthocyanidin extract targets p66Shc to regulate mitochondrial biogenesis and dynamics in diabetic kidney disease |
Omega-3 Fatty Acids | 📋 | ✍ | ⛔ | | 38464414 | The effects of omega-3 fatty acids supplementation on hemoglobin, hematocrit, and platelet levels of patients with ESRD condition undergoing dialysis |
Selenium | 📋 | ✍ | ⛔ | | 38432121 | Selenium protects against Pb-induced renal oxidative injury in weaning rats and human renal tubular epithelial cells through activating NRF2 |
Vitamin E | 📋 | ✍ | ⛔ | | 38290470 | Effect of Vitamin E on Diabetic Nephropathy: A Meta-Analysis |
Silymarin | 📋 | ✍ | ⛔ | | 38700358 | Therapeutic Potential of Silymarin in Mitigating Paclitaxel-Induced Hepatotoxicity and Nephrotoxicity: Insights into Oxidative Stress, Inflammation, and Apoptosis in Rats |
Astaxanthin | 📋 | ✍ | ⛔ | | 38720817 | Ameliorative impacts of astaxanthin against atrazine-induced renal toxicity through the modulation of ionic homeostasis and Nrf2 signaling pathways in mice |
Fucoidan | 📋 | ✍ | ⛔ | | 38635872 | Fucoidan Improves Early Stage Diabetic Nephropathy via the Gut Microbiota-Mitochondria Axis in High-Fat Diet-Induced Diabetic Mice |
L-Carnitine | 📋 | ✍ | ⛔ | | 38322874 | Protective effects of l-carnitine on isoprenaline -induced heart and kidney dysfunctions: Modulation of inflammation and oxidative stress-related gene expression in rats |
Puerarin | 📋 | ✍ | ⛔ | | 38308547 | Inhibition of Pyroptosis of Renal Tubular Epithelial Cells by Puerarin via Regulation of lncRNA NEAT1 Ameliorating Chronic Renal Failure |
Ellagic Acid | 📋 | ✍ | ⛔ | | 38465322 | Renal protection by ellagic acid in a rat model of glycerol-induced acute kidney injury |
CoQ10 | 📋 | ✍ | ⛔ | | 38716935 | Protective effect of coenzyme Q10 in cyclophosphamide-induced kidney damage in rats |
Luteolin | 📋 | ✍ | ⛔ | | 36362919 | An In-Silico Identification of Potential Flavonoids against Kidney Fibrosis Targeting TGFβR-1 |
Cordyceps | 📋 | ✍ | ⛔ | | 38517396 | Cordyceps sinensis extract protects against acute kidney injury by inhibiting perforin expression in NK cells via the STING/IRF3 pathway |
Naringenin | 📋 | ✍ | ⛔ | | 38345349 | NARINGENIN'S EFFECTS ON DIURESIS AND PREVENTION OF UROLITHIASIS IN HYPERTENSIVE RATS |
Salidroside | 📋 | | | | 38259279 | Pharmacological functions of salidroside in renal diseases: facts and perspectives |
Stinging Nettle | 📋 | ✍ | ⛔ | | 38716323 | Efficacy of an Oral Solution Containing Five Herbal Extracts in the Treatment of Urolithiasis: A Randomized, Single-blind, Placebo-controlled Clinical Trial |
Crocin | 📋 | ✍ | ⛔ | | 38662441 | Crocin, the compound of the dried stigma of Crocus sativus L (saffron), restores doxorubicin-induced disturbances in kidney functioning, oxidative stress, inflammation, renal tissue morphology and TGF-β signalling pathways |
Genistein | 📋 | ✍ | ⛔ | | 36932924 | Genistein attenuates renal ischemia-reperfusion injury via ADORA2A pathway |
Hesperidin | 📋 | ✍ | ⛔ | | 38548778 | Cyclosporine-induced kidney damage was halted by sitagliptin and hesperidin via increasing Nrf2 and suppressing TNF-α, NF-κB, and Bax |
Icariin | 📋 | ✍ | | | 38583082 | Icariin alleviates renal inflammation and tubulointerstitial fibrosis via Nrf2-mediated attenuation of mitochondrial damage |
Salvianolic Acid | 📋 | | | | 38070193 | Salvianolic acid B attenuates diabetic nephropathy through alleviating ADORA2B, NALP3 inflammasome, and NFκB activity |
Chrysin | 📋 | ✍ | ⛔ | | 37716503 | Chrysin attenuates paclitaxel-induced hepatorenal toxicity in rats by suppressing oxidative damage, inflammation, and apoptosis |
Ginkgo Biloba | 📋 | ✍ | ⛔ | | 37087791 | Ginkgo biloba extract attenuates cisplatin-induced renal interstitial fibrosis by inhibiting the activation of renal fibroblasts through down-regulating the HIF-1α/STAT3/IL-6 pathway in renal tubular epithelial cells |
Gallic Acid | 📋 | | ⛔ | | 38184176 | Evaluation of antibacterial, antifungal and antibiofilm activities of A. baumannii-derived tannase and gallic acid against uropathogenic microorganisms |
Mangiferin | 📋 | | ⛔ | | 38094010 | Mangiferin alleviates renal inflammatory injury in spontaneously hypertensive rats by inhibiting MCP-1/CCR2 signaling pathway |
Moringa Oleifera | 📋 | ✍ | ⛔ | | 36584917 | Moringa oleifera impedes protein glycation and exerts reno-protective effects in streptozotocin-induced diabetic rats |
Allicin | 📋 | ✍ | ⛔ | | 37830900 | Allicin Alleviates Mitochondrial Dysfunction in Acrylamide-Induced Rat Kidney Involving the Regulation of SIRT1 |
Angelica | 📋 | ✍ | ⛔ | | 38404557 | The effect of Astragali Radix-Radix Angelica Sinensis on acute kidney injury: a network pharmacology and molecular docking study |
Baicalin | 📋 | ✍ | ⛔ | | 38132855 | Baicalin Exhibits a Protective Effect against Cisplatin-Induced Cytotoxic Damage in Canine Renal Tubular Epithelial Cells |
Bee Propolis | 📋 | ✍ | ⛔ | | 38419887 | Propolis and its therapeutic effects on renal diseases: A review |
Emodin | 📋 | | ⛔ | | 38504574 | The Role of Emodin in the Treatment of Bladder Cancer based on Network Pharmacology and Experimental Verification |
Fisetin | 📋 | ✍ | ⛔ | | 38426151 | Fisetin enhances cisplatin sensitivity in renal cell carcinoma via the CDK6/PI3K/Akt/mTOR signaling pathway |
Rutin | 📋 | ✍ | ⛔ | | 38479315 | Rutin mitigates fluoride-induced nephrotoxicity by inhibiting ROS-mediated lysosomal membrane permeabilization and the GSDME-HMGB1 axis involved in pyroptosis and inflammation |
Silibinin | 📋 | ✍ | | | 38164275 | Role of heat shock protein 70 in silibinin-induced apoptosis in bladder cancer |
Diosmin | 📋 | ✍ | ⛔ | | 38195573 | Diosmin ameliorates renal fibrosis through inhibition of inflammation by regulating SIRT3-mediated NF-κB p65 nuclear translocation |
Lipoic Acid | 📋 | ✍ | ⛔ | | 37378741 | Antioxidant and Anti-inflammatory Effects of α-Lipoic Acid on Lipopolysaccharide-induced Oxidative Stress in Rat Kidney |
Pterostilbene | 📋 | ✍ | ⛔ | | 37566321 | Protective potential of pterostilbene against cyclophosphamide-induced nephrotoxicity and cystitis in rats |
Reishi Mushrooms | 📋 | ✍ | ⛔ | | 37841924 | Therapeutic potential of Ganoderma lucidum polysaccharide peptide in Doxorubicin-induced nephropathy: modulation of renin-angiotensin system and proteinuria |
TUDCA | 📋 | ✍ | ⛔ | | 38518722 | Exploring the impact of high-altitude de-acclimatization on renal function: The roles of oxidative and endoplasmic reticulum stress in rat models |
Zinc | 📋 | ✍ | ⛔ | | 37805879 | TESTOSTERONE AND SERUM ZINC LEVELS IN MEN WITH BENIGN PROSTATIC HYPERPLASIA |
D-Mannose | 📋 | ✍ | ⛔ | | 37630763 | Novel Key Ingredients in Urinary Tract Health-The Role of D-mannose, Chondroitin Sulphate, Hyaluronic Acid, and N-acetylcysteine in Urinary Tract Infections (Uroial PLUS®) |
Kaempferol | 📋 | ✍ | ⛔ | | 36530875 | Kaempferol attenuated diabetic nephropathy by reducing apoptosis and promoting autophagy through AMPK/mTOR pathways |
Medicinal Plants | 📋 | | | | 38532487 | Medicinal plants and natural products for treating overactive bladder |
Nobiletin | 📋 | ✍ | | | 38563051 | Nobiletin alleviates methotrexate-induced hepatorenal toxicity in rats |
Red Sage | 📋 | ✍ | ⛔ | | 38380573 | Effect and pharmacological mechanism of Salvia miltiorrhiza and its characteristic extracts on diabetic nephropathy |
Roselle | 📋 | ✍ | ⛔ | | 38708257 | Nephroprotective Effect of Hibiscus Sabdariffa Leaf Flavonoid Extracts via KIM-1 and TGF-1β Signaling Pathways in Streptozotocin-Induced Rats |
Tanshinone | 📋 | | | | 38650121 | Tanshinone IIA suppresses ferroptosis to attenuate renal podocyte injury in diabetic nephropathy through the embryonic lethal abnormal visual-like protein 1 and acyl-coenzyme A synthetase long-chain family member 4 signaling pathway |
Pine Bark | 📋 | ✍ | ⛔ | | 35916821 | Effect of pycnogenol on ethanol-related oxidative retinal injury: an experimental study |
Pomegranate | 📋 | | ⛔ | | 38027401 | Possible role of pomegranate fruit in reversing renal damage in rats exposed to Phenylhydrazine |
Tribulus Terrestris | 📋 | ✍ | ⛔ | | 38716323 | Efficacy of an Oral Solution Containing Five Herbal Extracts in the Treatment of Urolithiasis: A Randomized, Single-blind, Placebo-controlled Clinical Trial |
Asiatic Acid | 📋 | | | | 37413899 | Asiatic acid alleviates cisplatin-induced renal fibrosis in tumor-bearing mice by improving the TFEB-mediated autophagy-lysosome pathway |
NMN | 📋 | ✍ | ⛔ | | 36046029 | Restoration of NAD+ homeostasis protects C2C12 myoblasts and mouse levator ani muscle from mechanical stress-induced damage |
Food | 📋 | | | | 38429831 | Association between dietary phytochemical index and risk of benign prostatic hyperplasia: a case-control study |
Honokiol | 📋 | | | | 37898101 | A novel combination therapy with Cabozantinib and Honokiol effectively inhibits c-Met-Nrf2-induced renal tumor growth through increased oxidative stress |
Naringin | 📋 | ✍ | ⛔ | | 38037725 | Naringin attenuates oxaliplatin-induced nephrotoxicity and hepatotoxicity: A molecular, biochemical, and histopathological approach in a rat model |
Phytochemicals | 📋 | | | | 37569752 | Diabetic Nephropathy: Significance of Determining Oxidative Stress and Opportunities for Antioxidant Therapies |
Pumpkin Seed | 📋 | ✍ | ⛔ | | 38213175 | Deciphering Multi-target Pharmacological Mechanism of Cucurbita pepo Seeds against Kidney Stones: Network Pharmacology and Molecular Docking Approach |
Cannabidiol | 📋 | ✍ | ⛔ | | 36902479 | Cannabidiol as a Promising Therapeutic Option in IC/BPS: In Vitro Evaluation of Its Protective Effects against Inflammation and Oxidative Stress |
Capsaicin | 📋 | ✍ | ⛔ | | 38700794 | Capsaicin reduces blood glucose and prevents prostate growth by regulating androgen, RAGE/IGF-1/Akt, TGF-β/Smad signalling pathway and reversing epithelial-mesenchymal transition in streptozotocin-induced diabetic mice |
Formononetin | 📋 | | | | 37288590 | Comparative transcriptomic analysis and mechanistic characterization revealed the use of formononetin for bladder cancer treatment |
Galangin | 📋 | | | | 36305128 | Network-based pharmacology and in vitro validation reveal that galangin induces apoptosis in bladder cancer cells by promoting the p53 signaling pathway |
Goji Berry | 📋 | ✍ | ⛔ | | 37722516 | Intervention effect of Lycium barbarum polysaccharide on lead-induced kidney injury mice and its mechanism: A study based on the PI3K/Akt/mTOR signaling pathway |
Micronutrients | 📋 | | ⛔ | | 38474096 | Therapeutic Effect of Natural Products and Dietary Supplements on Aflatoxin-Induced Nephropathy |
Vitamin K | 📋 | ✍ | ⛔ | | 36138326 | Dysbiosis in Patients with Chronic Kidney Disease: Let Us Talk About Vitamin K |
Acai Berry | 📋 | ✍ | ⛔ | | 36460743 | Polyphenol-rich açaà seed extract exhibits reno-protective and anti-fibrotic activities in renal tubular cells and mice with kidney failure |
Caffeine | 📋 | ✍ | ⛔ | | 37799542 | Caffeine causes cell cycle arrest at G0/G1 and increases of ubiquitinated proteins, ATP and mitochondrial membrane potential in renal cells |
Chondroitin | 📋 | ✍ | ⛔ | | 38721680 | Oral preparation of hyaluronic acid, chondroitin sulfate, N-acetylglucosamine, and vitamin C improves sexual and urinary symptoms in participants with recurrent urinary tract infections: a randomized crossover trial |
Cinnamon | 📋 | ✍ | ⛔ | | 38669415 | Exploring the mechanism of action of the combination of cinnamon and motherwort in the treatment of benign prostatic hyperplasia: A network pharmacology study |
Cornus | 📋 | | | | 38606866 | Ethanol Extracts of Cornus alba Improve Benign Prostatic Hyperplasia by Inhibiting Prostate Cell Proliferation through Modulating 5 Alpha-Reductase/Androgen Receptor Axis-Mediated Signaling |
Gotu Kola | 📋 | ✍ | ⛔ | | 36124918 | Inhibitory effects of Centella asiatica (L.) Urban on enlarged prostate through androgen receptor and PI3K/Akt signaling pathways |
L-Carnosine | 📋 | ✍ | ⛔ | | 38081616 | [Carnosine protects against diabetic nephropathy in rats by activating the AKT/mTOR pathway and restoring autophagy in the renal tissue] |
Licochalcones | 📋 | | | | 36840005 | Licochalcone A Suppresses Renal Cancer Cell Proliferation and Metastasis by Engagement of Sp1-Mediated LC3 Expression |
Olive Oil | 📋 | ✍ | ⛔ | | 37673343 | The potential protectivity of honey and olive oil in methotrexate induced renal damage in rats |
Ollive Leaf extract | 📋 | ✍ | ⛔ | | 37497380 | Ameliorative Effect of Olea europaea Leaf Extract on Cisplatin-Induced Nephrotoxicity in the Rat Model |
Vitamin A | 📋 | ✍ | ⛔ | | 37463986 | Retinol intake is associated with the risk of chronic kidney disease in individuals with type 2 diabetes mellitus: results from NHANES |
Amygdalin | 📋 | ✍ | ⛔ | | 34278886 | Metabolomics reveals the renoprotective effect of n-butanol extract and amygdalin extract from Amygdalus mongolica in rats with renal fibrosis |
Betulinic Acid | 📋 | | | | 37631096 | Protective Role of Betulinic Acid against Cisplatin-Induced Nephrotoxicity and Its Antibacterial Potential toward Uropathogenic Bacteria |
Carvacrol | 📋 | ✍ | ⛔ | | 38256015 | Oregano ( Origanum vulgare) Essential Oil and Its Constituents Prevent Rat Kidney Tissue Injury and Inflammation Induced by a High Dose of L-Arginine |
Coffee | 📋 | ✍ | ⛔ | | 38160137 | Coffee consumption and risk of kidney function decline in a Dutch population-based cohort |
Ferulic Acid | 📋 | ✍ | ⛔ | | 37724953 | Renoprotective effects of ferulic acid mediated by AMPKα1 against lipopolysaccharide-induced damage |
Frankincense | 📋 | ✍ | ⛔ | | 37334022 | Effects of frankincense on experimentally induced renal stones in rats |
Modified Citrus Pectin | 📋 | ✍ | ⛔ | | 38588017 | Modified Citrus Pectin (MCP) Confers a Renoprotective Effect on Early-Stage Nephropathy in Type-2 Diabetic Mice |
Oleuropein | 📋 | | | | 38582273 | Oleuropein attenuates the nephrotoxic effect of sunitinib in rats: Unraveling the potential role of SIRT6/Notch-1/NLRP-3/IL-1β axis |
Probiotics | 📋 | ✍ | ⛔ | | 38558739 | Exploring the Impact of Optimized Probiotic Supplementation Techniques on Diabetic Nephropathy: Mechanisms and Therapeutic Potential |
Rosmarinic Acid | 📋 | ✍ | | | 38376274 | Protective effect of rosmarinic acid on the transmembrane transporter Ctr1 expression in cisplatin-treated mice |
Tea | 📋 | | | | 38428885 | Impact of habitual intake of glucosamine, fresh fruit, and tea on the risk of urolithiasis: A two-sample Mendelian randomization study |
Arctigenin | 📋 | | | | 38215692 | Additive renal protective effects between arctigenin and puerarin in diabetic kidney disease |
Baicalein | 📋 | ✍ | ⛔ | | 38601597 | Baicalein improves renal interstitial fibrosis by inhibiting the ferroptosis in vivo and in vitro |
Butyrate | 📋 | | ⛔ | | 38358014 | Sodium butyrate ameliorated diabetic nephropathy-associated tubulointerstitial inflammation by modulating the tight junctions of renal tubular epithelial cells |
Cinnamaldehyde | 📋 | | | | 37839279 | Cytoprotective effects of cinnamaldehyde and adipoRon against cyclophosphamide-induced cardio-renal toxicity in rats: Insights into oxidative stress, inflammation, and apoptosis |
Daidzein | 📋 | ✍ | ⛔ | | 37378389 | The effect of daidzein on renal injury in ovariectomized rats: interaction of angiotensin receptors and long non-coding RNAs H19, GAS5, MIAT, and Rian |
Dandelion | 📋 | ✍ | ⛔ | | 38674879 | Effects of Taraxaci Herba (Dandelion) on Testosterone Propionate-Induced Benign Prostatic Hyperplasia in Rats |
Date | 📋 | | ⛔ | | 38529813 | Water-soluble phenolics from Phoenix dactylifera fruits as potential reno-protective agent against cisplatin-induced toxicity: pre- and post-treatment strategies |
Dihydromyricetin | 📋 | ✍ | ⛔ | | 38035992 | Dihydromyricetin protects against gentamicin-induced nephrotoxicity via upregulation of renal SIRT3 and PAX2 |
Eicosapentaenoic Acid | 📋 | ✍ | ⛔ | | 34977254 | Protective Effects of Eicosapentaenoic Acid on the Glomerular Endothelium via Inhibition of EndMT in Diabetes |
Hesperetin | 📋 | | | | 38357946 | Hesperetin Inhibits Bladder Cancer Cell Proliferation and Promotes Apoptosis and Cycle Arrest by PI3K/AKT/FoxO3a and ER Stress-mitochondria Pathways |
Licorice Root | 📋 | ✍ | ⛔ | | 37692489 | Echinatin inhibits tumor growth and synergizes with chemotherapeutic agents against human bladder cancer cells by activating p38 and suppressing Wnt/β-catenin pathways |
Pomegranate Peel extract | 📋 | ✍ | ⛔ | | 38213945 | Methanol Crude Peel Extract of P. granatum Prevents Oxidative Damage in Kidneys of Rats Exposed to Highly Active Antiretroviral Therapy |
Tangeretin | 📋 | | | | 37354638 | Connexin43 is associated with the progression of clear cell renal carcinoma and is regulated by tangeretin to sygergize with tyrosine kinase inhibitors |
Telmisartan | 📋 | | ⛔ | | 38074815 | Telmisartan combined with calcitriol enhances therapeutic efficacy for diabetic nephropathy while inhibiting inflammation and renal interstitial fibrosis |
Vitamin B9 | 📋 | ✍ | ⛔ | | 38326739 | Impact of folic acid supplementation on ischemia‒reperfusion-induced kidney injury in rats: folic acid prophylactic role revisited |
Catalpol | 📋 | | | | 38325797 | Catalpol ameliorates fructose-induced renal inflammation by inhibiting TLR4/MyD88 signaling and uric acid reabsorption |
Dihydroquercetin | 📋 | | | | 36769524 | Renoprotective Effect of Taxifolin in Paracetamol-Induced Nephrotoxicity: Emerging Evidence from an Animal Model |
Docosahexaenoic Acid | 📋 | ✍ | ⛔ | | 36875087 | Lipidome modulation by dietary omega-3 polyunsaturated fatty acid supplementation or selective soluble epoxide hydrolase inhibition suppresses rough LPS-accelerated glomerulonephritis in lupus-prone mice |
Fish Oil | 📋 | ✍ | ⛔ | | 38065716 | Habitual fish oil supplementation, genetic susceptibility of kidney stones and the risk of new-onset kidney stones |
Fucoxanthin | 📋 | ✍ | ⛔ | | 35126819 | Fucoxanthin Attenuates Oxidative Damage by Activating the Sirt1/Nrf2/HO-1 Signaling Pathway to Protect the Kidney from Ischemia-Reperfusion Injury |
Gingerol | 📋 | ✍ | | | 35919815 | [6]-Gingerol induces Caspase-Dependent Apoptosis in Bladder Cancer cells via MAPK and ROS Signaling |
Green Tea | 📋 | ✍ | ⛔ | | 37594507 | Effect of fluid replacement with green tea on body fluid balance and renal responses under mild thermal hypohydration: a randomized crossover study |
Hyaluronic Acid | 📋 | ✍ | ⛔ | | 38721680 | Oral preparation of hyaluronic acid, chondroitin sulfate, N-acetylglucosamine, and vitamin C improves sexual and urinary symptoms in participants with recurrent urinary tract infections: a randomized crossover trial |
Hyperoside | 📋 | | | | 38464829 | Hyperoside induces cell cycle arrest and suppresses tumorigenesis in bladder cancer through the interaction of EGFR-Ras and Fas signaling pathways |
Indian Gooseberry | 📋 | | ⛔ | | 36034880 | Phyllanthus Niruri L. Exerts Protective Effects Against the Calcium Oxalate-Induced Renal Injury via Ellgic Acid |
L-Glutamine | 📋 | ✍ | ⛔ | | 37851784 | L-glutamine supplementation reduced morphological damage in the renal glomerulus of rats with Walker-256 tumor |
Paeoniflorin | 📋 | | | | 37884904 | Paeoniflorin alleviates hypoxia/reoxygenation injury in HK-2 cells by inhibiting apoptosis and repressing oxidative damage via Keap1/Nrf2/HO-1 pathway |
Pumpkin Seed Oil | 📋 | ✍ | ⛔ | | 34984064 | Phytosterols in hull-less pumpkin seed oil, rich in ∆ 7-phytosterols, ameliorate benign prostatic hyperplasia by lowing 5α-reductase and regulating balance between cell proliferation and apoptosis in rats |
Rhubarb | 📋 | | ⛔ | | 38340950 | Herb pair of Rhubarb-Astragalus mitigates renal interstitial fibrosis through downregulation of autophagy via p38-MAPK/TGF-β1 and p38-MAPK/smad2/3 pathways |
Saffron | 📋 | ✍ | ⛔ | | 35656071 | Saffron nephroprotective effects against medications and toxins: A review of preclinical data |
Taurine | 📋 | ✍ | ⛔ | | 37805666 | The renoprotective effects of taurine against diabetic nephropathy via the p38 MAPK and TGF-β/Smad2/3 signaling pathways |
Aged Garlic | 📋 | ✍ | ⛔ | | 35366767 | S-Allylcysteine (SAC) Exerts Renoprotective Effects via Regulation of TGF- β1/Smad3 Pathway Mediated Matrix Remodeling in Chronic Renal Failure |
Chokeberry | 📋 | ✍ | ⛔ | | 37511414 | The Protective Potential of Aronia melanocarpa L. Berry Extract against Cadmium-Induced Kidney Damage: A Study in an Animal Model of Human Environmental Exposure to This Toxic Element |
Echinacea | 📋 | ✍ | ⛔ | | 38467789 | Immuno-antioxidative reno-modulatory effectiveness of Echinacea purpurea extract against bifenthrin-induced renal poisoning |
Green Tea Polyphenols | 📋 | ✍ | ⛔ | | 37734331 | Green tea polyphenols alleviate kidney injury induced by di(2-ethylhexyl) phthalate in mice |
Inulin | 📋 | ✍ | ⛔ | | 38725443 | Inulin Reduces Kidney Damage in Type 2 Diabetic Mice by Decreasing Inflammation and Serum Metabolomics |
L-Arginine | 📋 | ✍ | ⛔ | | 37450015 | Cannabinoid receptor 2 (CB2) agonists and L-arginine ameliorate diabetic nephropathy in rats by suppressing inflammation and fibrosis through NF-κβ pathway |
Mulberry | 📋 | | ⛔ | | 37732507 | Mulberry leaf extract and neochlorogenic acid ameliorate glucolipotoxicity-induced diabetic nephropathy in high-fat diet-fed db/db mice |
NAD | 📋 | | | | 37592796 | NAD+ Protects Against Hyperlipidemia‑induced Kidney Injury in Apolipoprotein E‑deficient Mice |
Neferine | 📋 | | | | 38658442 | Neferine alleviates acute kidney injury by regulating the PPAR-α/NF-κB pathway |
Polyphenols | 📋 | | | | 37635982 | Regulation of autophagy by natural polyphenols in the treatment of diabetic kidney disease: therapeutic potential and mechanism |
Pomegranate Seed extract | 📋 | | ⛔ | | 38065332 | Pomegranate Seed Oil Mitigates Liver and Kidney Damage in an Experimental Colitis Model: Modulation of NF-κB Activation and Apoptosis |
Schisandrins | 📋 | | | | 38382281 | Schisandrin A alleviates renal fibrosis by inhibiting PKCβ and oxidative stress |
Wogonin | 📋 | ✍ | ⛔ | | 34295152 | Wogonin Alleviates Kidney Tubular Epithelial Injury in Diabetic Nephropathy by Inhibiting PI3K/Akt/NF-κB Signaling Pathways |
Andrographolide | 📋 | | | | 33000263 | Andrographolide sensitizes human renal carcinoma cells to TRAIL‑induced apoptosis through upregulation of death receptor 4 |
Anthocyanins | 📋 | ✍ | ⛔ | | 36335368 | Anthocyanin improves kidney function in diabetic kidney disease by regulating amino acid metabolism |
Arjuna | 📋 | ✍ | ⛔ | | 34919901 | Arjunolic acid downregulates elevated blood sugar and pro-inflammatory cytokines in streptozotocin (STZ)-nicotinamide induced type 2 diabetic rats |
Ashwagandha | 📋 | ✍ | ⛔ | | 37663806 | Protective impacts of Withania somnifera leaf extract from Taif area against diclofenac induced hepato-renal toxicity: role of antioxidants, inflammation, apoptosis, and anti-oxidative stress biomarkers |
Barberry | 📋 | ✍ | ⛔ | | 35427583 | Berberis integerrima hydro-alcoholic root extract ant its constituent berberine protect against cisplatin-induced nephro- and hepato-toxicity |
Boswellic Acid | 📋 | ✍ | ⛔ | | 38718656 | Boswellic acid and apigenin alleviate methotrexate-provoked renal and hippocampal alterations in rats: Targeting autophagy, NOD-2/NF-κB/NLRP3, and connexin-43 |
Catechins | 📋 | | | | 38687305 | (+)-Catechin ameliorates diabetic nephropathy injury by inhibiting endoplasmic reticulum stress-related NLRP3-mediated inflammation |
Diosgenin | 📋 | | | | 37630743 | Diosgenin Targets CaMKK2 to Alleviate Type II Diabetic Nephropathy through Improving Autophagy, Mitophagy and Mitochondrial Dynamics |
Geraniol | 📋 | | | | 38362098 | The Inhibitory Effect of Geraniol on CCL4-induced Hepatorenal Toxicity in Pregnant Mice through the PI3K/AKT Signaling Pathway |
Ginger extract | 📋 | ✍ | ⛔ | | 37174437 | Protective Effect of Quercetin and Ginger ( Zingiber officinale) Extract against Dimethoate Potentiated Fluoride-Induced Nephrotoxicity in Rats |
Ginkgolides | 📋 | | | | 37715308 | Ginkgolide A downregulates transient receptor potential (melastatin) 2 to protect cisplatin-induced acute kidney injury in rats through the TWEAK/Fn14 pathway: Ginkgolide A improve acute renal injury |
Glycyrrhizic Acid | 📋 | ✍ | ⛔ | | 37648177 | The protective effect and molecular mechanism of glycyrrhizic acid glycosides against Tripterygium glycosides induced nephrotoxicity based on the RhoA/ROCK1 signalling pathway |
Lemon | 📋 | | ⛔ | | 37799616 | Antibacterial Activity of Selected Fruit Juices against Multidrug-Resistant Bacterial Pathogens Involved in Urinary Tract and Sexually Transmitted Infections among Tribal Women in Madhya Pradesh, India |
Linalool | 📋 | | ⛔ | | 38294506 | Monoterpene linalool restrains gentamicin-mediated acute kidney injury in rats by subsiding oxidative stress, apoptosis, and the NF-κB/iNOS/TNF-α/IL-1β pathway and regulating TGF-β |
Mangosteen | 📋 | ✍ | ⛔ | | 34316206 | Ameliorative effect of Mangosteen ( Garcinia mangostana L.) peel infusion on the histopathological structures of the liver and kidney of rats ( Rattus norvegicus Berkenhout, 1769) after H 2 O 2 induction |
Myricetin | 📋 | | ⛔ | | 38313853 | Myricetin induces M2 macrophage polarization to alleviate renal tubulointerstitial fibrosis in diabetic nephropathy via PI3K/Akt pathway |
Nicotinamide | 📋 | ✍ | ⛔ | | 38446387 | Nicotinamide protects against diabetic kidney disease through regulation of Sirt1 |
Phloretin | 📋 | | | | 37722590 | Phloretin as an add-on therapy to losartan attenuates diabetes-induced AKI in rats: A potential therapeutic approach targeting TLR4-induced inflammation |
PQQ | 📋 | ✍ | ⛔ | | 35489281 | Pyrroloquinoline quinone ameliorates renal fibrosis in diabetic nephropathy by inhibiting the pyroptosis pathway in C57BL/6 mice and human kidney 2 cells |
Pygeum Africanum | 📋 | ✍ | ⛔ | | 35435166 | [Effectiveness of treatment with Pygeum africanum in patients with lower urinary tract symptoms and benign prostatic hyperplasia: a cross-sectional study in the real-world clinical practice in Spain (The PROFIT Study)] |
Rehmannia | 📋 | ✍ | ⛔ | | 37579922 | Rehmannia glutinosa Libosch and Cornus officinalis Sieb herb couple ameliorates renal interstitial fibrosis in CKD rats by inhibiting the TGF-β1/MAPK signaling pathway |
Rice | 📋 | | ⛔ | | 36379906 | Resistant starch from black rice, Oryza sativa L. var. ameliorates renal inflammation, fibrosis and injury in insulin resistant rats |
Star Fuit | 📋 | | ⛔ | | 31972423 | 2-Dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione, isolated from the root of Averrhoa carambola L., protects against diabetic kidney disease by inhibiting TLR4/TGFβ signaling pathway |
Tannic Acid | 📋 | ✍ | ⛔ | | 38393487 | Cyto and Genoprotective Potential of Tannic Acid Against Cadmium and Nickel Co-exposure Induced Hepato-Renal Toxicity in BALB/c Mice |
Tomato | 📋 | | ⛔ | | 37726932 | Selenium in combination with a tomato lipid extract as a therapy for benign prostatic hyperplasia and its alterations in rats with induced BPH |
Andrographis | 📋 | ✍ | ⛔ | | 35196932 | Andrographis paniculata mitigates first-line anti-tubercular drugs-induced nephrotoxicity in Wistar rats |
Artemisinin | 📋 | | | | 37309415 | Exploration of Artemisinin Against IgA Nephropathy via AKT/Nrf2 Pathway by Bioinformatics and Experimental Validation |
Beta-Sitosterol | 📋 | ✍ | ⛔ | | 38148931 | The use of beta-sitosterol for the treatment of prostate cancer and benign prostatic hyperplasia |
Biochanin A | 📋 | | | | 37237918 | Biochanin A Ameliorates Nephropathy in High-Fat Diet/Streptozotocin-Induced Diabetic Rats: Effects on NF-kB/NLRP3 Axis, Pyroptosis, and Fibrosis |
Boric Acid | 📋 | ✍ | ⛔ | | 37562273 | Therapeutic role of boron on acrylamide-induced nephrotoxicity, cardiotoxicity, neurotoxicity, and testicular toxicity in rats: Effects on Nrf2/Keap-1 signaling pathway and oxidative stress |
Calycosin | 📋 | | | | 36278223 | Calycosin attenuates renal ischemia/reperfusion injury by suppressing NF-κB mediated inflammation via PPARγ/EGR1 pathway |
CAPE | 📋 | | | | 37588661 | The protective effect of caffeic acid phenethyl ester in the nephrotoxicity induced by α-cypermethrin |
Carotenoids | 📋 | ✍ | ⛔ | | 37740155 | Association of dietary carotenoid intake with the prevalence kidney stones among the general adult population |
Coconut Oil | 📋 | | ⛔ | | 32523886 | Nephroprotective activity of virgin coconut oil on diclofenac-induced oxidative nephrotoxicity is associated with antioxidant and anti-inflammatory effects in rats |
Coptis Chinensis | 📋 | | ⛔ | | 35095505 | Dissecting and Evaluating the Therapeutic Targets of Coptis Chinensis Franch in the Treatment of Urinary Tract Infections Induced by Escherichia coli |
Dioscin | 📋 | | | | 36960871 | Mechanism of dioscin ameliorating renal fibrosis through NF‑κB signaling pathway‑mediated inflammatory response |
Flavonoids | 📋 | | ⛔ | | 37200367 | Comprehensive in silico analyses of flavonoids elucidating the drug properties against kidney disease by targeting AIM2 |
Folate | 📋 | ✍ | ⛔ | | 37630806 | Folate Deficiency Enhanced Inflammation and Exacerbated Renal Fibrosis in High-Fat High-Fructose Diet-Fed Mice |
Grape | 📋 | | ⛔ | | 35046823 | Proanthocyanidins Protect Against Cadmium-Induced Diabetic Nephropathy Through p38 MAPK and Keap1/Nrf2 Signaling Pathways |
Graviola | 📋 | ✍ | ⛔ | | 38362149 | Annona Muricata L. extract restores renal function, oxidative stress, immunohistochemical structure, and gene expression of TNF-α, IL-β1, and CYP2E1 in the kidney of DMBA-intoxicated rats |
Hydroxytyrosol | 📋 | | | | 37699441 | Modulation of mi-RNA25/Ox-LDL/NOX4 signaling pathway by polyphenolic compound Hydroxytyrosol as a new avenue to alleviate cisplatin-induced acute kidney injury, a mechanistic study in rats |
Onion | 📋 | ✍ | ⛔ | | 37928042 | The protective effect of allium cepa against ethylene glycol-induced kidney stones in rats |
Polydatin | 📋 | ✍ | | | 37793278 | Polydatin protects against calcium oxalate crystal-induced renal injury through the cytoplasmic/mitochondrial reactive oxygen species-NLRP3 inflammasome pathway |
Punicalagin | 📋 | ✍ | ⛔ | | 34989745 | Punicalagin alleviates renal injury via the gut-kidney axis in high-fat diet-induced diabetic mice |
Retinoic Acid | 📋 | | | | 38539513 | The Effect of Retinoic Acid on Arsenite-Transformed Malignant UROtsa Bladder Cancer Cells: In Vitro Model of Basal Muscle-Invasive Bladder Cancer |
Shogaol | 📋 | | | | 38329001 | [6]-Shogaol Induces Apoptosis of Murine Bladder Cancer Cells |
Soy Isoflavones | 📋 | ✍ | ⛔ | | 34236368 | Effects of soy isoflavone supplementation on patients with diabetic nephropathy: a systematic review and meta-analysis of randomized controlled trials |
Spirulina | 📋 | ✍ | ⛔ | | 35237421 | The protective impacts of Spirulina platensis against cisplatin-induced renal injury through the regulation of oxidative stress, pro-inflammatory cytokines and Bax/Bcl2 |
St. Johns Wort | 📋 | ✍ | ⛔ | | 33981220 | Hypericum perforatum L. Regulates Glutathione Redox Stress and Normalizes Ggt1/Anpep Signaling to Alleviate OVX-Induced Kidney Dysfunction |
Tetrahydrocurcumin | 📋 | ✍ | | | 34474516 | Tetrahydrocurcumin Ameliorates Kidney Injury and High Systolic Blood Pressure in High-Fat Diet-Induced Type 2 Diabetic Mice |
Thymol | 📋 | ✍ | ⛔ | | 38256015 | Oregano ( Origanum vulgare) Essential Oil and Its Constituents Prevent Rat Kidney Tissue Injury and Inflammation Induced by a High Dose of L-Arginine |
Urolithins | 📋 | | | | 36010548 | Urolithins Modulate the Viability, Autophagy, Apoptosis, and Nephrin Turnover in Podocytes Exposed to High Glucose |
Ursolic Acid | 📋 | ✍ | ⛔ | | 38443785 | The potential mechanism of ursolic acid in the treatment of bladder cancer based on network pharmacology and molecular docking |
Vitamin B6 | 📋 | ✍ | ⛔ | | 36976348 | Micronutrient inadequacy and urinary stone disease: an analysis of the National Health and Nutrition Examination Survey 2007-2018 |
Zingerone | 📋 | | | | 36822304 | Zingerone reduces sodium arsenite-induced nephrotoxicity by regulating oxidative stress, inflammation, apoptosis and histopathological changes |
Argan Oil | 📋 | ✍ | ⛔ | | 33114212 | The Antioxidant, Anti-Apoptotic, and Proliferative Potency of Argan Oil against Betamethasone-Induced Oxidative Renal Damage in Rats |
Beets | 📋 | ✍ | ⛔ | | 34613396 | Pink pressure: beetroot (Beta vulgaris rubra) as a possible novel medical therapy for chronic kidney disease |
Betaine | 📋 | ✍ | ⛔ | | 38713257 | Modulation of the Nrf-2 and HO-1 signalling axis is associated with Betaine's abatement of fluoride-induced hepatorenal toxicities in rats |
Cantaloupe | 📋 | | ⛔ | | 38716323 | Efficacy of an Oral Solution Containing Five Herbal Extracts in the Treatment of Urolithiasis: A Randomized, Single-blind, Placebo-controlled Clinical Trial |
Cardamonin | 📋 | | | | 38585526 | Cardamonin mitigates kidney injury by modulating inflammation, oxidative stress, and apoptotic signaling in rats subjected to renal ischemia and reperfusion |
Carnosic Acid | 📋 | | | | 31752142 | Carnosic Acid Attenuates Cadmium Induced Nephrotoxicity by Inhibiting Oxidative Stress, Promoting Nrf2/HO-1 Signalling and Impairing TGF-β1/Smad/Collagen IV Signalling |
Cat's Claw | 📋 | ✍ | ⛔ | | 26154141 | The Quinovic Acid Glycosides Purified Fraction from Uncaria tomentosa Protects against Hemorrhagic Cystitis Induced by Cyclophosphamide in Mice |
Chaga Mushrooms | 📋 | ✍ | ⛔ | | 38161352 | Research Progress on Application of Inonotus obliquus in Diabetic Kidney Disease |
Chlorogenic Acid | 📋 | ✍ | ⛔ | | 36986437 | TLR4/Inflammasomes Cross-Talk and Pyroptosis Contribute to N-Acetyl Cysteine and Chlorogenic Acid Protection against Cisplatin-Induced Nephrotoxicity |
Cocoa | 📋 | ✍ | ⛔ | | 37324470 | Computational and experimental pharmacology to decode the efficacy of Theobroma cacao L. against doxorubicin-induced organ toxicity in EAC-mediated solid tumor-induced mice |
Conjugated Linoleic Acid | 📋 | ✍ | ⛔ | | 36545457 | Effect of Conjugated Linoleic Acid (CLA) Supplementation on Expression of B-Cell Lymphoma-2 (Bcl-2) in the Bladder Epithelium of Wistar (Rattus norvegicus) Rats Exposed to Cigarette Smoke |
Cordycepin | 📋 | | | | 38014886 | Cordycepin inhibits kidney injury by regulating GSK-3β-mediated Nrf2 activation |
Corn Silk | 📋 | ✍ | ⛔ | | 38716323 | Efficacy of an Oral Solution Containing Five Herbal Extracts in the Treatment of Urolithiasis: A Randomized, Single-blind, Placebo-controlled Clinical Trial |
Crocetin | 📋 | | | | 38057037 | Crocetin ameliorative effect on diabetic nephropathy in rats through a decrease in transforming growth factor-β and an increase in glyoxalase-I activity |
Cryptotanshinone | 📋 | | | | 36462735 | Cryptotanshinone modulates proliferation, apoptosis, and fibrosis through inhibiting AR and EGFR/STAT3 axis to ameliorate benign prostatic hyperplasia progression |
DHEA | 📋 | ✍ | ⛔ | | 35784547 | Low Serum Dehydroepiandrosterone Is Associated With Diabetic Kidney Disease in Men With Type 2 Diabetes Mellitus |
Diallyl Disulfide | 📋 | | | | 34084059 | Ameliorative Role of Diallyl Disulfide Against Glycerol-induced Nephrotoxicity in Rats |
Dihydroartemisinin | 📋 | | | | 38351420 | Dihydroartemisinin abolishes cisplatin-induced nephrotoxicity in vivo |
Escin | 📋 | ✍ | ⛔ | | 35215244 | Aescin Protects against Experimental Benign Prostatic Hyperplasia and Preserves Prostate Histomorphology in Rats via Suppression of Inflammatory Cytokines and COX-2 |
Fenugreek | 📋 | ✍ | ⛔ | | 35878267 | Fenugreek Seed Galactomannan Aqueous and Extract Protects against Diabetic Nephropathy and Liver Damage by Targeting NF-κB and Keap1/Nrf2 Axis |
Fruits | 📋 | | | | 38428885 | Impact of habitual intake of glucosamine, fresh fruit, and tea on the risk of urolithiasis: A two-sample Mendelian randomization study |
Geniposide | 📋 | | | | 38508092 | Geniposide reduced oxidative stress-induced apoptosis in HK-2 cell through PI3K/AKT3/FOXO1 by m6A modification |
Glucosamine | 📋 | ✍ | ⛔ | | 38428885 | Impact of habitual intake of glucosamine, fresh fruit, and tea on the risk of urolithiasis: A two-sample Mendelian randomization study |
Irisin | 📋 | | | | 38218331 | The role of irisin in kidney diseases |
Isoflavones | 📋 | ✍ | ⛔ | | 35807748 | Isoflavone Protects the Renal Tissue of Diabetic Ovariectomized Rats via PPARγ |
Isoliquiritigenin | 📋 | | | | 37561086 | Isoliquiritigenin pretreatment regulates ER stress and attenuates cisplatin-induced nephrotoxicity in male Wistar rats |
Isorhamnetin | 📋 | | | | 38466121 | Isorhamnetin ameliorates cisplatin-induced acute kidney injury in mice by activating SLPI-mediated anti-inflammatory effect in macrophage |
Knotweed | 📋 | ✍ | ⛔ | | 35176933 | Outcomes of a complementary and alternative medicine based on vitamins, herbal products, and amino acid as a first line treatment in idiopathic overactive bladder syndrome in men and women without bladder outlet obstruction |
L-Methionine | 📋 | ✍ | ⛔ | | 37931136 | L-methionine protects against nephrotoxicity induced by methotrexate through modulation of redox status and inflammation |
Ligustilide | 📋 | | | | 36921687 | Levistolide A ameliorates fibrosis in chronic kidney disease via modulating multitarget actions in vitro and in vivo |
Lotus | 📋 | | ⛔ | | 36501396 | In Vitro and In Vivo Nephroprotective Effects of Nelumbo nucifera Seedpod Extract against Cisplatin-Induced Renal Injury |
Magnolol | 📋 | | | | 37549536 | Unveiling nature's potential weapon: Magnolol's role in combating bladder cancer by upregulating the miR-124 and inactivating PKC-δ/ERK axis |
Marjoram | 📋 | | ⛔ | | 36723325 | ORIGANUM MAJORANA ATTENUATES CIPROFLOXACIN-INDUCED NEPHROPATHY IN RATS |
Nicotinamide Riboside | 📋 | ✍ | ⛔ | | 38464264 | Nicotinamide riboside activates renal metabolism and protects the kidney in a model of Alport syndrome |
Oleanolic Acid | 📋 | | | | 38668524 | Oleanolic Acid Acetate Alleviates Cisplatin-Induced Nephrotoxicity via Inhibition of Apoptosis and Necroptosis In Vitro and In Vivo |
Orange | 📋 | | ⛔ | | 32466228 | Effects of a Red Orange and Lemon Extract in Obese Diabetic Zucker Rats: Role of Nicotinamide Adenine Dinucleotide Phosphate Oxidase |
Paeonol | 📋 | | | | 35185559 | Paeonol Protects Against Methotrexate-Induced Nephrotoxicity via Upregulation of P-gp Expression and Inhibition of TLR4/NF-κB Pathway |
Piperine | 📋 | ✍ | ⛔ | | 33134133 | Protective effect of piperine in ischemia-reperfusion induced acute kidney injury through inhibition of inflammation and oxidative stress |
Poria Mushrooms | 📋 | ✍ | | | 31452866 | Combined melatonin and poricoic acid A inhibits renal fibrosis through modulating the interaction of Smad3 and β-catenin pathway in AKI-to-CKD continuum |
Potassium | 📋 | ✍ | ⛔ | | 37330455 | Low Potassium Intake: A Common Risk Factor for Nephrolithiasis in Patients with High Blood Pressure |
Royal Jelly | 📋 | ✍ | ⛔ | | 38476622 | Royal Jelly, A Super Food, Protects Against Celecoxib-Induced Renal Toxicity in Adult Male Albino Rats |
Schisandra | 📋 | ✍ | ⛔ | | 36280016 | Network pharmacology analysis combined with experimental validation to explore the therapeutic mechanism of Schisandra Chinensis mixture on diabetic nephropathy |
Scutellarin | 📋 | | | | 38656633 | Scutellarin ameliorates diabetic nephropathy via TGF-β1 signaling pathway |
Theaflavins | 📋 | ✍ | | | 38171247 | Theaflavin pretreatment ameliorates renal ischemia/reperfusion injury by attenuating apoptosis and oxidative stress in vivo and in vitro |
Thyme Essential Oil | 📋 | | ⛔ | | 36337844 | The Effect of Thyme Essential Oil on Liver Injuries Caused by Renal Ischemia-Reperfusion in Rats |
Vitamin B Complex | 📋 | | ⛔ | | 38413451 | The Protective Effects of Vitamin B Complex on Diclofenac Sodium-Induced Nephrotoxicity: The Role of NOX4/RhoA/ROCK |
Vitamin B12 | 📋 | ✍ | ⛔ | | 34655350 | Evaluation by different mechanisms of the protective effects of vitamin B12 on methotrexate nephrotoxicity |
Vitexin | 📋 | | | | 37891461 | Vitexin attenuates chronic kidney disease by inhibiting renal tubular epithelial cell ferroptosis via NRF2 activation |
Withaferin A | 📋 | | | | 34209212 | Withaferin A Triggers Apoptosis and DNA Damage in Bladder Cancer J82 Cells through Oxidative Stress |
Activated Charcoal | 📋 | ✍ | ⛔ | | 38146721 | Effects of Increased Blood Flow Rate and Oral Activated Charcoal on the Severity of Uremic Pruritus: A Randomized Crossover Clinical Trial |
Antioxidants | 📋 | | ⛔ | | 37853637 | Association between an Antioxidant-Rich Japanese Diet and Chronic Kidney Disease: The Ohasama Study |
Arctiin | 📋 | | | | 33118522 | [Arctiin antagonizes triptolide-induced renal toxicity in rats via anti-inflammatory pathway] |
Asiaticoside | 📋 | | | | 37539103 | Asiaticoside ameliorates renal ischemia/reperfusion injury by promoting CD4+CD25+FOXP3+ treg cell differentiation |
Asparagus | 📋 | | ⛔ | | 37837591 | Renal-protective effect of Asparagus officinalis aqueous extract against lead-induced nephrotoxicity mouse model |
Aspirin | 📋 | | ⛔ | | 37838641 | Association of low-dose aspirin use for primary prevention with self-reported kidney stones prevalence: a cross-sectional study |
Avocado Oil | 📋 | | ⛔ | | 34832999 | Avocado Oil Prevents Kidney Injury and Normalizes Renal Vasodilation after Adrenergic Stimulation in Hypertensive Rats: Probable Role of Improvement in Mitochondrial Dysfunction and Oxidative Stress |
Bacopa Monnieri | 📋 | ✍ | ⛔ | | 35956923 | Antibacterial Potential of Bacopa monnieri (L.) Wettst. and Its Bioactive Molecules against Uropathogens-An In Silico Study to Identify Potential Lead Molecule(s) for the Development of New Drugs to Treat Urinary Tract Infections |
Balloon Flower | 📋 | ✍ | ⛔ | | 37146841 | Platycodin D inhibits HFD/STZ-induced diabetic nephropathy via inflammatory and apoptotic signaling pathways in C57BL/6 mice |
Bee Pollen | 📋 | ✍ | ⛔ | | 35589738 | Protective effect of bee pollen in acute kidney injury, proteinuria, and crystalluria induced by ethylene glycol ingestion in rats |
Bee Venom | 📋 | ✍ | ⛔ | | 38584815 | Melittin induces autophagy to alleviate chronic renal failure in 5/6-nephrectomized rats and angiotensin II-induced damage in podocytes |
Bilberry | 📋 | ✍ | ⛔ | | 32864929 | The Role of Vaccinium Myrtillus in the Prevention of Renal Injury in an Experimental Model of Ruptured Abdominal Aortic Aneurysm |
Blackcurrant | 📋 | ✍ | ⛔ | | 34601083 | Renoprotective activity of Ribes diacanthum pall (RDP) against inflammation in cisplatin-stimulated mice model and human renal tubular epithelial cells |
Caffeic Acid | 📋 | ✍ | ⛔ | | 38102533 | The Hepatorenal Protective Potential of Caffeic Acid Consumption on the Arsenic-Exposed Syrian Mice |
Carrot | 📋 | | ⛔ | | 34949157 | The nephroprotective effects of Daucus carota and Eclipta prostrata against cisplatin-induced nephrotoxicity in rats |
Chamomile Essential Oil | 📋 | ✍ | ⛔ | | 34833945 | The Impact of Selected Essential Oils Applied to Non-Woven Viscose on Bacteria That Cause Lower Urinary Tract Infections-Preliminary Studies |
Cinnamon Essential Oil | 📋 | ✍ | ⛔ | | 33679180 | Renoprotective effects of cinnamon oil against APAP-Induced nephrotoxicity by ameliorating oxidative stress, apoptosis and inflammation in rats |
Clove | 📋 | | ⛔ | | 34367514 | Antioxidant-rich Clove Extract, A Strong Antimicrobial Agent against Urinary Tract Infections-causing Bacteria in vitro |
Cyanidin | 📋 | ✍ | | | 33551679 | The Protective Effect of Anthocyanins Extracted from Aronia Melanocarpa Berry in Renal Ischemia-Reperfusion Injury in Mice |
Diallyl Trisulfide | 📋 | | | | 38128310 | Diallyl trisulfide and its active metabolite allyl methyl sulfone attenuate cisplatin-induced nephrotoxicity by inhibiting the ROS/MAPK/NF-κB pathway |
Eucalyptol | 📋 | | | | 38115227 | Eucalyptol regulates Nrf2 and NF-kB signaling and alleviates gentamicin-induced kidney injury in rats by downregulating oxidative stress, oxidative DNA damage, inflammation, and apoptosis |
Fiber | 📋 | ✍ | ⛔ | | 38707305 | Association between dietary fiber intake and diabetic nephropathy among adult diabetes mellitus in the United States: A cross-sectional study |
Fig | 📋 | | ⛔ | | 32946057 | Synergistic effects of Ficus Carica extract and extra virgin olive oil against oxidative injury, cytokine liberation, and inflammation mediated by 5-Fluorouracil in cardiac and renal tissues of male albino rats |
Flaxseed | 📋 | ✍ | ⛔ | | 34665824 | Effect of flaxseed on systemic inflammation and oxidative stress in diabetic rats with or without chronic kidney disease |
Garlic | 📋 | ✍ | ⛔ | | 38051214 | Evidential support for garlic supplements against diabetic kidney disease: a preclinical meta-analysis and systematic review |
Ginger | 📋 | ✍ | ⛔ | | 36369018 | Renoprotective effects of the ginger (Zingiber officinale) on Diabetic kidney disease, current knowledge and future direction: a systematic review of animal studies |
Ginkgetin | 📋 | | | | 34148304 | Ginkgetin alleviates high glucose-evoked mesangial cell oxidative stress injury, inflammation, and extracellular matrix (ECM) deposition in an AMPK/mTOR-mediated autophagy axis |
Guggulsterone | 📋 | | | | 35123992 | Z-Guggulsterone alleviates renal fibrosis by mitigating G2/M cycle arrest through Klotho/p53 signaling |
Haritaki | 📋 | ✍ | ⛔ | | 38159820 | The Terminalia chebula Retz extract treats hyperuricemic nephropathy by inhibiting TLR4/MyD88/NF-κB axis |
Hawthorn | 📋 | ✍ | ⛔ | | 36076481 | Interval training and Crataegus persica ameliorate diabetic nephropathy via miR-126/Nrf-2 mediated inhibition of stress oxidative in rats with diabetes after myocardial ischemia-reperfusion injury |
Honey | 📋 | ✍ | ⛔ | | 37673343 | The potential protectivity of honey and olive oil in methotrexate induced renal damage in rats |
Jujube | 📋 | | ⛔ | | 37245086 | Hydroalcoholic Extract of Ziziphus Jujuba Leaf to Prevent Ethylene Glycol and Ammonium Chloride-Induced Kidney Stones in Male Rat: Is it Effective? |
Kudzu Root | 📋 | ✍ | ⛔ | | 34514791 | Metabolic Profiling of Carbonyl Compounds for Unveiling Protective Mechanisms of Pueraria lobata against Diabetic Nephropathy by UPLC-Q-Orbitrap HRMS/MS Analysis |
L-Theanine | 📋 | ✍ | ⛔ | | 36415057 | L-Theanine Mitigates the Harmful Effects of Excess High-Protein Diet in Rats by Regulating Protein Metabolism |
Maitake Mushrooms | 📋 | | ⛔ | | 35616773 | Grifola frondosa Polysaccharide Ameliorates Early Diabetic Nephropathy by Suppressing the TLR4/NF-κB Pathway |
Motherwort | 📋 | ✍ | ⛔ | | 38669415 | Exploring the mechanism of action of the combination of cinnamon and motherwort in the treatment of benign prostatic hyperplasia: A network pharmacology study |
Myrrh | 📋 | ✍ | ⛔ | | 32279153 | Efficacy of Frankincense and Myrrha in Treatment of Acute Interstitial Cystitis/Painful Bladder Syndrome |
Nootkatone | 📋 | | | | 36829928 | Nootkatone Supplementation Attenuates Carbon Tetrachloride Exposure-Induced Nephrotoxicity in Mice |
Nuciferine | 📋 | | | | 38006352 | Nuciferine Protects against Obesity-Induced Nephrotoxicity through Its Hypolipidemic, Anti-Inflammatory, and Antioxidant Effects |
Oleic Acid | 📋 | | ⛔ | | 37738211 | Aging-Related Mitochondrial Dysfunction is Associated with Fibrosis in Benign Prostatic Hyperplasia |
Papaya | 📋 | ✍ | ⛔ | | 37360438 | Mercuric Chloride Induced Nephrotoxicity: Ameliorative Effect of Carica papaya Leaves Confirmed by Histopathology, Immunohistochemistry, and Gene Expression Studies |
Perilla | 📋 | ✍ | | | 37513901 | The Effects of Perilla frutescens Extracts on IgA Nephropathy: A Systematic Review and Meta-Analysis |
PUFA | 📋 | | | | 36356379 | Polyunsaturated fatty acids ameliorate renal stone-induced renal tubular damage via miR-93-5p/Pknox1 axis |
Rosemary | 📋 | ✍ | ⛔ | | 32206031 | Nephroprotective Effect of Green Tea, Rosmarinic Acid and Rosemary on N-diethylnitrosamine Initiated and Ferric Nitrilotriacetate Promoted Acute Renal Toxicity in Wistar Rats |
Rosemary Essential Oil | 📋 | ✍ | ⛔ | | 37016650 | Assessment of Effects of Rosemary Essential Oil on the Kidney Pathology of Diabetic Adult Male Albino Rats |
Sea Buckthorn | 📋 | ✍ | ⛔ | | 37614189 | Hippophae rhamnoides L. leaf extracts alleviate diabetic nephropathy via attenuation of advanced glycation end product-induced oxidative stress in db/db mice |
Sesamol | 📋 | | | | 38350822 | Protective Effects of Sesamol on Renal Ischemia-Reperfusion Injury Via Regulation of Nuclear Factor Erythroid 2-Related Factor 2 Pathway |
Skullcap | 📋 | ✍ | ⛔ | | 34149863 | Molecular Targets and Mechanisms of Scutellariae radix- Coptidis rhizoma Drug Pair for the Treatment of Ulcerative Colitis Based on Network Pharmacology and Molecular Docking |
Soy Protein | 📋 | ✍ | ⛔ | | 37693248 | Comparison of the effects of different percentages of soy protein in the diet on patients with type 2 diabetic nephropathy: systematic reviews and network meta-analysis |
Strawberry | 📋 | ✍ | ⛔ | | 30345090 | Determination of Antimicrobial Activity of Some Commercial Fruit (Apple, Papaya, Lemon and Strawberry) Against Bacteria Causing Urinary Tract Infection |
Tongkat Ali | 📋 | ✍ | ⛔ | | 37433989 | Eurycoma longifolia alkaloid components ameliorate hyperuricemic nephropathy via regulating serum uric acid level and relieving inflammatory reaction |
Vitamin B3 | 📋 | ✍ | ⛔ | | 35631221 | Association between Vitamin Intake and Chronic Kidney Disease According to a Variant Located Upstream of the PTGS1 Gene: A Cross-Sectional Analysis of Shika Study |
Vitamin K1 | 📋 | ✍ | ⛔ | | 31639794 | Vitamin K1 Inhibition of Renal Crystal Formation through Matrix Gla Protein in the Kidney |
Yam | 📋 | | | | 37856796 | Meta-analysis of Huangqi (Astragalus membranaceus) and Chinese Yam (Rhizoma Dioscoreae) for Diabetic Nephropathy |
Acacetin | 📋 | | | | 32175062 | Acacetin Attenuates Renal Damage-Induced by Ischemia-Reperfusion with Declining Apoptosis and Oxidative Stress in Mice |
Aloe Vera | 📋 | ✍ | ⛔ | | 29621403 | Amelioration of Diabetes-Induced Diabetic Nephropathy by Aloe Vera: Implication of Oxidative Stress and Hyperlipidemia |
Aloe-Emodin | 📋 | | | | 35518350 | Aloe-Emodin Ameliorates Diabetic Nephropathy by Targeting Interferon Regulatory Factor 4 |
Anethole | 📋 | | | | 36404830 | Renoprotective activity of anethole- rich fraction from aromatic herbs on junk food induced diabetic nephropathy in rats |
Apple | 📋 | | ⛔ | | 32820471 | Protective Effect of Grape and Apple Juices against Cadmium Intoxication in the Kidney of Rats |
Apple Vinegar | 📋 | ✍ | ⛔ | | 37090488 | GC-MS based metabolite profiling, antioxidant and antiurolithiatic properties of apple cider vinegar |
Arachidonic Acid | 📋 | ✍ | ⛔ | | 34940691 | Influence of Polyunsaturated Fatty Acid Intake on Kidney Functions of Rats with Chronic Renal Failure |
Astragalin | 📋 | | | | 36859596 | Astragalin ameliorates renal injury in diabetic mice by modulating mitochondrial quality control via AMPK-dependent PGC1α pathway |
Avocado | 📋 | ✍ | ⛔ | | 37871299 | Avocado Oil ( Persea americana) Reduces Epithelial Proliferation on Benign Prostatic Hyperplasia |
Basil | 📋 | ✍ | ⛔ | | 38150214 | Antioxidant and Protective Effect of Ocimum basilicum Seeds Extract on Renal Toxicity Induced by Carbon Tetrachloride in Rats |
Beta-Glucan | 📋 | ✍ | ⛔ | | 38444353 | β-Glucan ameliorates cisplatin-induced oxidative and histological damage in kidney and liver of rats |
Brazil Nut | 📋 | | ⛔ | | 30118536 | Inflammation and kidney injury attenuated by prior intake of Brazil nuts in the process of ischemia and reperfusion |
Bromelain | 📋 | ✍ | ⛔ | | 34630950 | Nutrition profile and potency of RGD motif in protein hydrolysate of green peas as an antifibrosis in chronic kidney disease |
Buckwheat | 📋 | | ⛔ | | 37150497 | Tartary buckwheat flavonoids alleviates high-fat diet induced kidney fibrosis in mice by inhibiting MAPK and TGF-β1/Smad signaling pathway |
Burdock | 📋 | | ⛔ | | 34955856 | Burdock Fructooligosaccharide Attenuates High Glucose-Induced Apoptosis and Oxidative Stress Injury in Renal Tubular Epithelial Cells |
Cabbage | 📋 | | ⛔ | | 37580924 | Study of ameliorative effect of Allium cepa essential oil and purple cabbage (Brassica Oleracea Var. Capitata F. Rubra) leaves extract on CCl4 induced nephrotoxicity in rats |
Calcium | 📋 | ✍ | ⛔ | | 35933132 | Dietary Risk Factors for Incident and Recurrent Symptomatic Kidney Stones |
Celery | 📋 | | ⛔ | | 35341158 | Cytoprotective Antioxidant, Anti-Inflammatory, and Antifibrotic Impact of Celery Seed Oil and Manuka Honey Against Cyclophosphamide-Induced Cystitis in Rabbits |
Chlorella | 📋 | ✍ | ⛔ | | 38704764 | Therapeutic potential of Lactobacillus casei and Chlorella vulgaris in high-fat diet-induced non-alcoholic fatty liver disease (NAFLD)-associated kidney damages: a stereological study |
Choline | 📋 | ✍ | ⛔ | | 38334759 | Effect of Dietary Choline Consumption on the Development of Urinary Urgency Incontinence in a Longitudinal Cohort of Women |
Chrysanthemum | 📋 | ✍ | ⛔ | | 35355712 | An Optimized Two-Herb Chinese Food as Medicine Formula Reduces Cisplatin-Induced Nephrotoxicity in the Treatment of Lung Cancer in Mice |
Citicoline | 📋 | ✍ | ⛔ | | 36519607 | Choline and citicoline ameliorate oxidative stress in acute kidney injury in rats |
Citrus Fruits | 📋 | | ⛔ | | 36658686 | Citrus fruit intake and incidence of renal cell carcinoma: A meta-analysis of observational studies |
Coconut | 📋 | | ⛔ | | 37975366 | Oral administration of naringenin and a mixture of coconut water and Arabic gum attenuate oxidative stress and lipid peroxidation in gentamicin-induced nephrotoxicity in rats |
Coriander | 📋 | | ⛔ | | 30845182 | Coriandrum sativum seeds extract mitigate progression of diabetic nephropathy in experimental rats via AGEs inhibition |
Costus | 📋 | ✍ | ⛔ | | 34486350 | Nephroprotective Effect of Costus ( Saussurea costus) Ethanolic Extract on Oxaliplatin ®-induced Nephrotoxicity in Adult Male Wistar Rats |
Diosmetin | 📋 | | | | 35119062 | Diosmin, a citrus fruit-derived phlebotonic bioflavonoid protects rats from chronic kidney disease-induced loss of bone mass and strength without deteriorating the renal function |
Eucommia | 📋 | ✍ | ⛔ | | 37517819 | Eucommia lignans alleviate the progression of diabetic nephropathy through mediating the AR/Nrf2/HO-1/AMPK axis in vivo and in vitro |
Eugenol | 📋 | | | | 36113730 | Nephroprotective potential of eugenol in a rat experimental model of chronic kidney injury; targeting NOX, TGF-β, and Akt signaling |
Evening Primrose Oil | 📋 | ✍ | ⛔ | | 23074118 | Gamma linolenic acid exerts anti-inflammatory and anti-fibrotic effects in diabetic nephropathy |
Fish | 📋 | | ⛔ | | 36411185 | Fatty foods and the risk of bladder cancer: A case-control study |
Fluted Gourd | 📋 | | | | 22654217 | Management of experimental benign prostatic hyperplasia in rats using a food-based therapy containing Telfairia occidentalis seeds |
Frankincense Essential Oil | 📋 | | ⛔ | | 25006348 | Differential effects of selective frankincense (Ru Xiang) essential oil versus non-selective sandalwood (Tan Xiang) essential oil on cultured bladder cancer cells: a microarray and bioinformatics study |
GABA | 📋 | ✍ | ⛔ | | 35714569 | GABA alleviates high glucose-induced podocyte injury through dynamically altering the expression of macrophage M1/M2-derived exosomal miR-21a-5p/miR-25-3p |
Ganoderic Acid | 📋 | | | | 34638569 | Ganoderic Acids Prevent Renal Ischemia Reperfusion Injury by Inhibiting Inflammation and Apoptosis |
Glabridin | 📋 | | | | 36098706 | Glabridin inhibits urothelial bladder carcinoma cell growth in vitro and in vivo by inducing cell apoptosis and cell cycle arrest |
Glycyrrhetinic Acid | 📋 | | | | 38222784 | Potential therapeutic targets for the prevention of diabetic nephropathy: Glycyrrhetinic acid |
Horsetail Grass | 📋 | ✍ | ⛔ | | 33747109 | Phytochemistry and Pharmacology of the Genus Equisetum (Equisetaceae): A Narrative Review of the Species with Therapeutic Potential for Kidney Diseases |
Krill Oil | 📋 | ✍ | ⛔ | | 35916281 | Krill Oil Turns Off TGF-β1 Profibrotic Signaling in the Prevention of Diabetic Nephropathy |
L-Histidine | 📋 | ✍ | ⛔ | | 33513395 | Protective effect of oral histidine on hypertension in Dahl salt-sensitive rats induced by high-salt diet |
L-Tryptophan | 📋 | ✍ | ⛔ | | 33287590 | Carcinogenesis and Bacillus Calmette-Guérin (BCG) Intravesical Treatment of Non-Muscle-Invasive Bladder Cancer under Tryptophan and Thymine Supplementation |
Lavender Essential Oil | 📋 | ✍ | ⛔ | | 35490236 | Anti-inflammatory effects of lavender and eucalyptus essential oils on the in vitro cell culture model of bladder pain syndrome using T24 cells |
Limonin | 📋 | | | | 37741252 | Limonin mitigates cisplatin-induced acute kidney injury through metabolic reprogramming |
Liquiritigenin | 📋 | | | | 35744945 | Protective Effects of Liquiritigenin against Cisplatin-Induced Nephrotoxicity via NRF2/SIRT3-Mediated Improvement of Mitochondrial Function |
Lutein | 📋 | ✍ | ⛔ | | 37755751 | Lutein Modulates Oxidative Stress, Inflammatory and Apoptotic Biomarkers Related to Di-(2-Ethylhexyl) Phthalate (DEHP) Hepato-Nephrotoxicity in Male Rats: Role of Nuclear Factor Kappa B |
Marigold | 📋 | ✍ | ⛔ | | 34229058 | Tagetes erecta L. flowers, a medicinal plant traditionally used to promote diuresis, induced diuretic and natriuretic effects in normotensive and hypertensive rats |
Matcha Tea | 📋 | | | | 38647648 | Comparative study of the anti-inflammatory activity of etoricoxib and Matcha green tea against acute kidney injury induced by gamma radiation in rats |
Milk Thistle | 📋 | ✍ | ⛔ | | 34630852 | Tackling of Renal Carcinogenesis in Wistar Rats by Silybum marianum Total Extract, Silymarin, and Silibinin via Modulation of Oxidative Stress, Apoptosis, Nrf2, PPAR γ, NF- κ B, and PI3K/Akt Signaling Pathways |
Mustard | 📋 | | ⛔ | | 37959024 | The Nephroprotective Potential of Brassica nigra Sprout Hydroalcoholic Extract against Carbon Tetrachloride-Induced Renal Toxicity in Rats |
Neem | 📋 | ✍ | | | 36522378 | Glucosidase inhibitor, Nimbidiol ameliorates renal fibrosis and dysfunction in type-1 diabetes |
Nimbolide | 📋 | | | | 35143824 | Co-treatment of Nimbolide augmented the anti-arthritic effects of methotrexate while protecting against organ toxicities |
Nuts | 📋 | | ⛔ | | 36411185 | Fatty foods and the risk of bladder cancer: A case-control study |
Oregano | 📋 | ✍ | ⛔ | | 34168532 | The antiurolithic activity of Origanum vulgare on rats treated with ethylene glycol and ammonium chloride: Possible pharmaco-biochemical and ultrastructure effects |
Parthenolide | 📋 | | | | 36985711 | Parthenolide Phytosomes Attenuated Gentamicin-Induced Nephrotoxicity in Rats via Activation of Sirt-1, Nrf2, OH-1, and NQO1 Axis |
PEA | 📋 | ✍ | ⛔ | | 34202665 | Palmitoylethanolamide/Baicalein Regulates the Androgen Receptor Signaling and NF-κB/Nrf2 Pathways in Benign Prostatic Hyperplasia |
Peas | 📋 | | ⛔ | | 34630950 | Nutrition profile and potency of RGD motif in protein hydrolysate of green peas as an antifibrosis in chronic kidney disease |
Peppermint | 📋 | ✍ | ⛔ | | 37900086 | The effect of nutritional factors on urolithiasis: A case-control study |
Peppermint Essential Oil | 📋 | ✍ | ⛔ | | 34836852 | Prophylactic and curative potential of peppermint oil against calcium oxalate kidney stones |
Persimmon | 📋 | | ⛔ | | 33522322 | Nephroprotective effect of persimmon leaves ( Diospyros kaki L.f.) against CCl 4-induced renal toxicity in Swiss Albino rats |
Piperlongumine | 📋 | | | | 37121453 | Piperlonguminine attenuates renal fibrosis by inhibiting TRPC6 |
Procyanidins | 📋 | | ⛔ | | 35861207 | Beneficial effects of procyanidin B2 on adriamycin-induced nephrotic syndrome mice: the multi-action mechanism for ameliorating glomerular permselectivity injury |
Pueraria Mirifica | 📋 | ✍ | ⛔ | | 30710233 | The effects of Pueraria mirifica extract, diadzein and genistein in testosterone-induced prostate hyperplasia in male Sprague Dawley rats |
Red Yeast Rice | 📋 | ✍ | ⛔ | | 33312555 | An antidiabetic nutraceutical combination of red yeast rice ( Monascus purpureus), bitter gourd ( Momordica charantia), and chromium alleviates dedifferentiation of pancreatic β cells in db/db mice |
Scutellarein | 📋 | | | | 34619498 | Scutellarein relieves the death and inflammation of tubular epithelial cells in ischemic kidney injury by degradation of COX-2 protein |
Sesame Oil | 📋 | | ⛔ | | 35532693 | Kidney dysfunction and oxidative stress in doxorubicin-induced nephrotic rat: Protective role of sesame oil |
Sesamin | 📋 | ✍ | | | 36232918 | The Protective Effects of Sesamin against Cyclophosphamide-Induced Nephrotoxicity through Modulation of Oxidative Stress, Inflammatory-Cytokines and Apoptosis in Rats |
Sodium Bicarbonate | 📋 | ✍ | ⛔ | | 37251318 | Effect of sodium bicarbonate on cardiovascular outcome and mortality in patients with advanced chronic kidney disease |
Soy | 📋 | ✍ | ⛔ | | 37081921 | Relationships of beans intake with chronic kidney disease in rural adults: A large-scale cross-sectional study |
Stevia | 📋 | ✍ | ⛔ | | 35820501 | High-throughput screening identifies stevioside as a potent agent to induce apoptosis in bladder cancer cells |
Syringic Acid | 📋 | | | | 36960519 | Nephroprotective potential of syringic acid in experimental diabetic nephropathy: Focus on oxidative stress and autophagy |
Taro Root | 📋 | | ⛔ | | 36873908 | In-vivo and in-silico studies revealed the molecular mechanisms of Colocasia esculenta phenolics as novel chemotherapy against benign prostatic hyperplasia via inhibition of 5α-reductase and α1-adrenoceptor |
Thyme | 📋 | ✍ | ⛔ | | 27973970 | Potential Renoprotective Effects of Rosemary and Thyme Against Gentamicin Toxicity in Rats |
Trehalose | 📋 | | ⛔ | | 35463818 | Effects of trehalose on NFE2L2, catalase, and superoxide dismutase in the kidney of aged rats |
Turmeric | 📋 | ✍ | ⛔ | | 35714209 | Efficacy and Safety of Turmeric Dietary Supplementation on Proteinuria in CKD: A Systematic Review and Meta-analysis of RCT |
Vegetables | 📋 | | | | 38408431 | Outcomes of a Dietary Intervention to Reduce Bladder Cancer Recurrence and Progression in Survivors of Non-Muscle-Invasive Bladder Cancer |
Vitamin K2 | 📋 | ✍ | ⛔ | | 32382009 | Vitamin K2 Promotes PI3K/AKT/HIF-1α-mediated Glycolysis That Leads to AMPK-dependent Autophagic Cell Death in Bladder Cancer Cells |
Vitamins | 📋 | | | | 37391399 | Vitamin D deficiency contributes to the diabetic kidney disease progression via increase ZEB1/ZEB2 expressions |
Walnut | 📋 | | ⛔ | | 30666075 | Juglans Regia L. Leaf Extract Attenuates Diabetic Nephropathy Progression in Experimental Diabetes: An Immunohistochemical Study |
Wormwood | 📋 | ✍ | ⛔ | | 36942132 | Hepatorenal protective activity of Artemisia against diclofenac toxicity in male rats |
Almond Oil | 📋 | | ⛔ | | 25992248 | The histological and histometrical effects of Urtica dioica extract on rat's prostate hyperplasia |
Aloin | 📋 | | | | 31254592 | Renal protective effects of aloin in a mouse model of sepsis |
Alpha-Linolenic Acid | 📋 | ✍ | ⛔ | | 38039041 | Alpha-linolenic acid protects against methotrexate-induced nephrotoxicity in mouse kidney cells |
Anise | 📋 | ✍ | ⛔ | | 27860049 | Pimpinella anisum L. ethanolic extract ameliorates the gentamicin- induced nephrotoxicity in rats |
Anthocyanidins | 📋 | | | | 36900199 | Dietary Intake of Anthocyanidins and Renal Cancer Risk: A Prospective Study |
Apricot Kernels | 📋 | ✍ | ⛔ | | 26781971 | Amygdalin Blocks the in Vitro Adhesion and Invasion of Renal Cell Carcinoma Cells by an Integrin-Dependent Mechanism |
Artichoke | 📋 | ✍ | ⛔ | | 38031637 | Protective effect of chicory and/or artichoke leaves extracts on carbon tetrachloride and gamma-irradiation-induced chronic nephrotoxicity in rats |
BCAA | 📋 | ✍ | ⛔ | | 32845566 | Regular exercise and branched-chain amino acids prevent ischemic acute kidney injury-related muscle wasting in mice |
Bean | 📋 | | ⛔ | | 37081921 | Relationships of beans intake with chronic kidney disease in rural adults: A large-scale cross-sectional study |
Bergamot | 📋 | ✍ | ⛔ | | 30884780 | Oxidative Imbalance and Kidney Damage in Cafeteria Diet-Induced Rat Model of Metabolic Syndrome: Effect of Bergamot Polyphenolic Fraction |
Beta-Cryptoxanthin | 📋 | | | | 36835262 | β-Cryptoxanthin Maintains Mitochondrial Function by Promoting NRF2 Nuclear Translocation to Inhibit Oxidative Stress-Induced Senescence in HK-2 Cells |
Beta-Lapachone | 📋 | | | | 16614704 | beta-lapachone induces growth inhibition and apoptosis in bladder cancer cells by modulation of Bcl-2 family and activation of caspases |
Bitter Melon | 📋 | ✍ | ⛔ | | 35023522 | The novel anti-inflammatory activity of mcIRBP from Momordica charantia is associated with the improvement of diabetic nephropathy |
Black Pepper | 📋 | ✍ | ⛔ | | 25572733 | Immunopathological and antimicrobial effect of black pepper, ginger and thyme extracts on experimental model of acute hematogenous pyelonephritis in albino rats |
Black Tea | 📋 | ✍ | ⛔ | | 35059399 | Isothiocyanate From Moringa oleifera Seeds Inhibits the Growth and Migration of Renal Cancer Cells by Regulating the PTP1B-dependent Src/Ras/Raf/ERK Signaling Pathway |
Blackberry | 📋 | | ⛔ | | 31040041 | Blackberry juice anthocyanidins limit cisplatin-induced renal pathophysiology in mice |
Blueberry | 📋 | ✍ | ⛔ | | 30865689 | The natural drug DIAVIT is protective in a type II mouse model of diabetic nephropathy |
Boron | 📋 | ✍ | ⛔ | | 31446563 | Boron, a Trace Mineral, Alleviates Gentamicin-Induced Nephrotoxicity in Rats |
Broccoli | 📋 | | ⛔ | | 35035501 | The Effect of Broccoli Extract in Arsenic-Induced Experimental Poisoning on the Hematological, Biochemical, and Electrophoretic Parameters of the Liver and Kidney of Rats |
Butter | 📋 | | ⛔ | | 37900086 | The effect of nutritional factors on urolithiasis: A case-control study |
Camellia | 📋 | | ⛔ | | 38068746 | Virgin Camellia Seed Oil Improves Glycolipid Metabolism in the Kidney of High Fat-Fed Rats through AMPK-SREBP Pathway |
Cannabidiol Oil | 📋 | ✍ | ⛔ | | 37971510 | Prospective affirmative therapeutics of cannabidiol oil mitigates doxorubicin-induced abnormalities in kidney function, inflammation, and renal tissue changes |
Captopril | 📋 | | | | 26398443 | Effects of Curcumin and Captopril on the Functions of Kidney and Nerve in Streptozotocin-Induced Diabetic Rats: Role of Angiotensin Converting Enzyme 1 |
Cardamom | 📋 | ✍ | ⛔ | | 37318456 | Protective effect of ethanolic extract of Elettaria Cardamomum against gentamicin hepato-renal toxicity in male albino rats |
Carnosol | 📋 | | | | 36552549 | Protective Effects of Carnosol on Renal Interstitial Fibrosis in a Murine Model of Unilateral Ureteral Obstruction |
Chamomile | 📋 | ✍ | ⛔ | | 34764746 | Chamomile flower extract ameliorates biochemical and histological kidney dysfunction associated with polycystic ovary syndrome |
Chicoric Acid | 📋 | | | | 38525833 | Chicoric acid advanced PAQR3 ubiquitination to ameliorate ferroptosis in diabetes nephropathy through the relieving of the interaction between PAQR3 and P110α pathway |
Chicory | 📋 | ✍ | ⛔ | | 38031637 | Protective effect of chicory and/or artichoke leaves extracts on carbon tetrachloride and gamma-irradiation-induced chronic nephrotoxicity in rats |
Chili Pepper | 📋 | | ⛔ | | 35176933 | Outcomes of a complementary and alternative medicine based on vitamins, herbal products, and amino acid as a first line treatment in idiopathic overactive bladder syndrome in men and women without bladder outlet obstruction |
Chromium | 📋 | ✍ | ⛔ | | 33312555 | An antidiabetic nutraceutical combination of red yeast rice ( Monascus purpureus), bitter gourd ( Momordica charantia), and chromium alleviates dedifferentiation of pancreatic β cells in db/db mice |
Cinnamic Acid | 📋 | | | | 38347789 | Uncovering the Mechanisms of Cinnamic Acid Treating Diabetic Nephropathy Based on Network Pharmacology, Molecular Docking, and Experimental Validation |
Colostrum | 📋 | ✍ | ⛔ | | 31805571 | A Prospective, Open-Label Comparison of Tamsulosin plus Serenoa repens and Bovine Colostrum versus Tamsulosin Alone in the Treatment of Benign Prostatic Hyperplasia |
Copper | 📋 | ✍ | ⛔ | | 36869998 | Association Between Serum Copper Levels and Urinary Incontinence in Adult Men |
Corn | 📋 | | ⛔ | | 35466676 | Purple Corn Extract Improves Benign Prostatic Hyperplasia by Regulating Prostate Cell Proliferation and Apoptosis |
Coumaric acid | 📋 | | | | 24060003 | p-Coumaric acid, a common dietary polyphenol, protects cadmium chloride-induced nephrotoxicity in rats |
Creatine | 📋 | ✍ | ⛔ | | 12969151 | Creatine Supplementation Decreases Homocysteine in an Animal Model of Uremia |
D-Limonene | 📋 | ✍ | ⛔ | | 33510839 | D-Limonene Alleviates Acute Kidney Injury Following Gentamicin Administration in Rats: Role of NF- κ B Pathway, Mitochondrial Apoptosis, Oxidative Stress, and PCNA |
Dairy | 📋 | | | | 36270480 | High-fat dairy products may decrease the risk of chronic kidney disease incidence: A long-term prospective cohort study |
Delphinidin | 📋 | | | | 30865689 | The natural drug DIAVIT is protective in a type II mouse model of diabetic nephropathy |
Diallyl Sulfide | 📋 | | | | 32785828 | Immunomodulatory effect of diallyl sulfide on experimentally-induced benign prostate hyperplasia via the suppression of CD4+T/IL-17 and TGF-β1/ERK pathways |
DIM | 📋 | ✍ | ⛔ | | 35283486 | Androgen receptor modulation and bladder cancer prevention - a short review |
Echinacoside | 📋 | | | | 35758826 | Echinacoside Ameliorates Cyclophosphamide-Induced Bladder Damage in Mice |
Eclipta Alba | 📋 | ✍ | | | 34949157 | The nephroprotective effects of Daucus carota and Eclipta prostrata against cisplatin-induced nephrotoxicity in rats |
Equol | 📋 | ✍ | ⛔ | | 19903517 | Comparison of Urodynamic Effects of Phytoestrogens Equol, Puerarin and Genistein With These of Estradiol 17beta in Ovariectomized Rats |
Eucalyptus | 📋 | ✍ | ⛔ | | 33134128 | Eucalyptus Globulus protects against diclofenac sodium induced hepatorenal and testicular toxicity in male rats |
Fennel | 📋 | ✍ | ⛔ | | 36829884 | Nephroprotective Effect of Fennel ( Foeniculum vulgare) Seeds and Their Sprouts on CCl4-Induced Nephrotoxicity and Oxidative Stress in Rats |
Fish Collagen | 📋 | ✍ | ⛔ | | 35223948 | Using Collagen Peptides From the Skin of Monkfish ( Lophius litulon) to Ameliorate Kidney Damage in High-Fat Diet Fed Mice by Regulating the Nrf2 Pathway and NLRP3 Signaling |
Flavones | 📋 | | | | 30903485 | Flavonoids and Bladder Cancer Risk |
Forskolin | 📋 | ✍ | ⛔ | | 35512548 | Forskolin alleviates cisplatin-induced acute renal toxicity in rats |
Galangal | 📋 | ✍ | ⛔ | | 37976696 | Multi-omic analysis revealed the therapeutic mechanisms of Alpinia oxyphylla fructus water extract against bladder overactivity in spontaneously hypertensive rats |
Gamma-Linolenic Acid | 📋 | ✍ | ⛔ | | 23074118 | Gamma linolenic acid exerts anti-inflammatory and anti-fibrotic effects in diabetic nephropathy |
Genipin | 📋 | | | | 33792721 | Effect of genipin-1-β-d-gentiobioside on diabetic nephropathy in mice by activating AMP-activated protein kinase/silencing information regulator-related enzyme 1/ nuclear factor-κB pathway |
Giloy | 📋 | ✍ | ⛔ | | 35383764 | Protective and Curative Effects of Ethanol extract of Tinospora Cordifolia on Gentamicin-induced Nephrotoxicity in Rats |
Ginkgolic Acid | 📋 | | | | 32256780 | Ginkgolic acid inhibits the growth of renal cell carcinoma cells via inactivation of the EGFR signaling pathway |
Grapefruit extract | 📋 | ✍ | ⛔ | | 15865506 | The effectiveness of grapefruit (Citrus paradisi) seeds in treating urinary tract infections |
Helichrysum | 📋 | | ⛔ | | 25617747 | Preventive treatment of calcium oxalate crystal deposition with immortal flowers |
Holy Basil | 📋 | ✍ | ⛔ | | 33642811 | The protective effect of Ocimum sanctum leaf extract against lead acetate-induced nephrotoxicity and hepatotoxicity in mice ( Mus musculus) |
Honeysuckle | 📋 | | ⛔ | | 35355712 | An Optimized Two-Herb Chinese Food as Medicine Formula Reduces Cisplatin-Induced Nephrotoxicity in the Treatment of Lung Cancer in Mice |
Hops | 📋 | ✍ | ⛔ | | 31261419 | Cucurbita pepo-Rhus aromatica-Humulus lupulus Combination Reduces Overactive Bladder Symptoms in Women - A Noninterventional Study |
Horny Goat Weed | 📋 | ✍ | ⛔ | | 34994765 | Total flavonoids in Epimedium koreanum Nakai alleviated chronic renal failure via promoting AMPK activation |
Horse Chestnut | 📋 | ✍ | ⛔ | | 27424320 | The efficacy of Aesculus hippocastanum seeds on diabetic nephropathy in a streptozotocin-induced diabetic rat model |
Hypericin | 📋 | | | | 38547517 | Hypericin alleviates Chronic Kidney Disease induced Left Ventricular Hypertrophy via regulation of FGF23-FGFR4 signaling pathway |
Iodine | 📋 | ✍ | ⛔ | | 33897162 | Single-dose instillation of povidone iodine for chyluria: A safe and effective therapy |
Isoquercitrin | 📋 | | | | 38666938 | In Silico and In Vitro Study of Isoquercitrin against Kidney Cancer and Inflammation by Triggering Potential Gene Targets |
Jasmine | 📋 | | ⛔ | | 36144196 | Metabolic Profiling of Jasminum grandiflorum L. Flowers and Protective Role against Cisplatin-Induced Nephrotoxicity: Network Pharmacology and In Vivo Validation |
Jojoba Oil | 📋 | ✍ | ⛔ | | 33481197 | Ameliorative effects of jojoba oil on fipronil-induced hepatorenal- and neuro-toxicity: the antioxidant status and apoptotic markers expression in rats |
Kacip Fatimah | 📋 | ✍ | ⛔ | | 21524700 | Labisia pumila var. alata reduces bacterial load by inducing uroepithelial cell apoptosis |
Kiwifruit | 📋 | ✍ | ⛔ | | 28759758 | Kiwi fruit (Actinidia deliciosa) ameliorates gentamicin-induced nephrotoxicity in albino mice via the activation of Nrf2 and the inhibition of NF-κB (Kiwi & gentamicin-induced nephrotoxicity) |
L-Alanine | 📋 | ✍ | ⛔ | | 33454690 | THE EFFECTS OF L-ORNITINE AND L-ARGININE ON THE PROCESSES OF LIPID PEROXIDATION IN THE FUNCTIONAL LAYERS OF KIDNEYS ON THE BACKGROUND OF ACUTE TOXIC HEPATITIS |
L-Lysine | 📋 | ✍ | ⛔ | | 36132073 | L-Lysine Ameliorates Diabetic Nephropathy in Rats with Streptozotocin-Induced Diabetes Mellitus |
L-Ornithine | 📋 | ✍ | ⛔ | | 33454690 | THE EFFECTS OF L-ORNITINE AND L-ARGININE ON THE PROCESSES OF LIPID PEROXIDATION IN THE FUNCTIONAL LAYERS OF KIDNEYS ON THE BACKGROUND OF ACUTE TOXIC HEPATITIS |
Lentil | 📋 | | ⛔ | | 36438775 | Antioxidative potential and ameliorative effects of green lentil ( Lens culinaris M.) sprouts against CCl4-induced oxidative stress in rats |
Lettuce | 📋 | | ⛔ | | 35392648 | Lettuce as an Effective Remedy in Uremic Pruritus: Review of the Literature Supplemented by an In Silico Study |
Lime Essential Oil | 📋 | ✍ | ⛔ | | 31662741 | Histoprotective Effect of Essential Oil from Citrus aurantifolia in Testosterone-Induced Benign Prostatic Hyperplasia Rat |
Lingonberry | 📋 | | ⛔ | | 32292787 | Inhibition of Inflammatory Cytokine Expression Prevents High-Fat Diet-Induced Kidney Injury: Role of Lingonberry Supplementation |
Loquat | 📋 | ✍ | ⛔ | | 37498560 | Polyphenol-rich extract from loquat fruit peel prevents hyperlipidemia and hepato-nephrotoxicity in mice: in vivo study and in silico prediction of possible mechanisms involving identified polyphenols and/or their circulating metabolites |
Lychee | 📋 | | ⛔ | | 33470120 | Polyphenol-Rich Extract from Litchi chinensis Seeds Alleviates Hypertension-Induced Renal Damage in Rats |
Maca Root | 📋 | ✍ | ⛔ | | 28635053 | Protective Effects of Lepidium meyenii (Maca) Aqueous Extract and Lycopene on Testosterone Propionate-Induced Prostatic Hyperplasia in Mice |
Madecassoside | 📋 | | | | 38056145 | Madecassoside alleviates acute kidney injury by regulating JNK-mediated oxidative stress and programmed cell death |
Magnolia | 📋 | ✍ | ⛔ | | 17671727 | Aqueous extract of Magnolia officinalis mediates proliferative capacity, p21WAF1 expression and TNF-alpha-induced NF-kappaB activity in human urinary bladder cancer 5637 cells; involvement of p38 MAP kinase |
Milk | 📋 | | ⛔ | | 36270480 | High-fat dairy products may decrease the risk of chronic kidney disease incidence: A long-term prospective cohort study |
Morusin | 📋 | | | | 32355771 | Morusin exerts anti-cancer activity in renal cell carcinoma by disturbing MAPK signaling pathways |
MSM | 📋 | ✍ | ⛔ | | 24402583 | Combination of AG490, a Jak2 inhibitor, and methylsulfonylmethane synergistically suppresses bladder tumor growth via the Jak2/STAT3 pathway |
Mucuna Pruriens | 📋 | ✍ | ⛔ | | 34789221 | Ethanolic extract of Mucuna pruriens leaves ameliorates carbon tetrachloride and rifampicin-induced hepatotoxicity and nephrotoxicity in wistar albino rat |
Myrrh Essential Oil | 📋 | | ⛔ | | 36826023 | Myrrh Essential Oil Mitigates Renal Ischemia/Reperfusion-Induced Injury |
Myrtle | 📋 | ✍ | ⛔ | | 33475094 | Myrtus communis improves cognitive impairment in renovascular hypertensive rats |
Nattokinase | 📋 | ✍ | ⛔ | | 30788657 | Nattokinase-heparin exhibits beneficial efficacy and safety-an optimal strategy for CKD patients on hemodialysis |
Neohesperidin | 📋 | | | | 36608504 | Neohesperidin dihydrochalbazone protects against septic acute kidney injury in mice |
Nutmeg | 📋 | ✍ | ⛔ | | 30519527 | Efficacy of mace (Arils of Myristica fragrans Houtt) plus PFMT on symptoms in mixed urinary incontinence: a randomized placebo-controlled trial |
Oats | 📋 | | ⛔ | | 35614982 | Oat β Glucan Ameliorates Renal Function and Gut Microbiota in Diabetic Rats |
Okra | 📋 | | ⛔ | | 36276416 | The effect of Abelmoschus esculentus L. (Okra) extract supplementation on dietary intake, appetite, anthropometric measures, and body composition in patients with diabetic nephropathy |
Oregano Essential Oil | 📋 | ✍ | ⛔ | | 38256015 | Oregano ( Origanum vulgare) Essential Oil and Its Constituents Prevent Rat Kidney Tissue Injury and Inflammation Induced by a High Dose of L-Arginine |
Patchouli | 📋 | ✍ | ⛔ | | 37177974 | Patchouli alcohol against renal fibrosis of spontaneously hypertensive rats via Ras/Raf-1/ERK1/2 signalling pathway |
Peach | 📋 | | ⛔ | | 33604381 | Using Network Pharmacology to Explore the Mechanism of Peach Kernel-Safflower in the Treatment of Diabetic Nephropathy |
Peanut | 📋 | | ⛔ | | 32202087 | Peanut Sprout Extracts Cultivated with Fermented Sawdust Medium Inhibits Benign Prostatic Hyperplasia In Vitro and In Vivo |
Peony | 📋 | | ⛔ | | 37599498 | Paeony attenuates high fat diet-induced kidney injury via inflammation inhibition |
Phellodendron | 📋 | ✍ | ⛔ | | 34735909 | The bioactive alkaloids identified from Cortex Phellodendri ameliorate benign prostatic hyperplasia via LOX-5/COX-2 pathways |
Phosphatidylserine | 📋 | ✍ | ⛔ | | 37666289 | Investigation of the potential ameliorative effects of DHA-enriched phosphatidylserine on bisphenol A-induced murine nephrotoxicity |
Phytosterols | 📋 | | | | 34984064 | Phytosterols in hull-less pumpkin seed oil, rich in ∆ 7-phytosterols, ameliorate benign prostatic hyperplasia by lowing 5α-reductase and regulating balance between cell proliferation and apoptosis in rats |
Pineapple | 📋 | ✍ | ⛔ | | 33583802 | Antinephrolithiatic activity of Ananas comosus extract against experimentally induced renal calculi in rats |
Prebiotics | 📋 | ✍ | ⛔ | | 36618701 | Association between probiotic, prebiotic, and yogurt consumption and chronic kidney disease: The NHANES 2010-2020 |
Proanthocyanidins | 📋 | | | | 36935438 | Effects of grape seed-derived proanthocyanidin B2 pretreatment on oxidative stress, endoplasmic reticulum stress and apoptosis of renal tubular epithelial cells in renal ischemia-reperfusion injury model of mice |
Progesterone | 📋 | ✍ | ⛔ | | 33739310 | Hormone therapy as a possible solution for postmenopausal women with nocturia: results of a pilot trial |
Protein | 📋 | ✍ | ⛔ | | 37211392 | Total protein intake and subsequent risk of chronic kidney disease: the Circulatory Risk in Communities Study |
Psyllium | 📋 | ✍ | ⛔ | | 37017261 | Psyllium seed husk regulates the gut microbiota and improves mucosal barrier injury in the colon to attenuate renal injury in 5/6 nephrectomy rats |
Pu-erh Tea | 📋 | ✍ | ⛔ | | 22482420 | Inhibition of advanced glycation end product formation by Pu-erh tea ameliorates progression of experimental diabetic nephropathy |
Rapamycin | 📋 | ✍ | | | 35783514 | Evaluation of a Dual PI3K/mTOR Inhibitor PF-04691502 against Bladder Cancer Cells |
Raspberry | 📋 | ✍ | ⛔ | | 37571251 | Effects of Unripe Black Raspberry Extract Supplementation on Male Climacteric Syndrome and Voiding Dysfunction: A Pilot, Randomized, Double-Blind, Placebo-Controlled Trial |
Rhodiola | 📋 | ✍ | ⛔ | | 37370698 | The Potent Anti-Tumor Effects of Rhodiola Drinking Are Associated with the Inhibition of the mTOR Pathway and Modification of Tumor Metabolism in the UPII-Mutant Ha-Ras Model |
Rosehip | 📋 | ✍ | ⛔ | | 34135957 | Protective Effects of Hydroalcoholic Extract of Rosa canina Fruit on Vancomycin-Induced Nephrotoxicity in Rats |
Safflower | 📋 | ✍ | ⛔ | | 33604381 | Using Network Pharmacology to Explore the Mechanism of Peach Kernel-Safflower in the Treatment of Diabetic Nephropathy |
Safranal | 📋 | | | | 26468467 | Histopathological and Behavioral Evaluations of the Effects of Crocin, Safranal and Insulin on Diabetic Peripheral Neuropathy in Rats |
Sage Essential Oil | 📋 | | ⛔ | | 30056541 | Carbon tetrachloride induced hepato/renal toxicity in experimental mice: antioxidant potential of Egyptian Salvia officinalis L essential oil |
Sandalwood Essential Oil | 📋 | | ⛔ | | 25006348 | Differential effects of selective frankincense (Ru Xiang) essential oil versus non-selective sandalwood (Tan Xiang) essential oil on cultured bladder cancer cells: a microarray and bioinformatics study |
Seafood | 📋 | | | | 36653033 | Association of omega 3 polyunsaturated fatty acids with incident chronic kidney disease: pooled analysis of 19 cohorts |
Seaweeds | 📋 | | ⛔ | | 35525730 | Sulfated Undaria pinnatifida polysaccharide inhibits the formation of kidney stones by inhibiting HK-2 cell damage and reducing the adhesion of nano‑calcium oxalate crystals |
Senolytics | 📋 | | | | 36384564 | The diseased kidney: aging and senescent immunology |
Sesame | 📋 | ✍ | ⛔ | | 32432778 | Sesame lignans suppress age-related disorders of the kidney in mice |
Sesamolin | 📋 | | | | 36630317 | Sesamolin Attenuates Kidney Injury, Intestinal Barrier Dysfunction, and Gut Microbiota Imbalance in High-Fat and High-Fructose Diet-Fed Mice |
Shiitake Mushrooms | 📋 | ✍ | ⛔ | | 38417905 | The Tumor Growth Inhibitory Effect of a Standardized Extract of Cultured Lentinula edodes Mycelia Using Patient Derived Xenograft Model |
Shilajit | 📋 | ✍ | ⛔ | | 34799663 | Mumio (Shilajit) as a potential chemotherapeutic for the urinary bladder cancer treatment |
Sirtuin Activators | 📋 | | | | 35774140 | Sirtuin Family and Diabetic Kidney Disease |
Spermidine | 📋 | | | | 37380734 | Spermidine from arginine metabolism activates Nrf2 and inhibits kidney fibrosis |
Stigmasterol | 📋 | | | | 27784187 | Renoprotective effect of Bacopa monnieri via inhibition of advanced glycation end products and oxidative stress in STZ-nicotinamide-induced diabetic nephropathy |
Sulfur | 📋 | ✍ | ⛔ | | 37367846 | Sulfur-Containing Amino Acids, Hydrogen Sulfide, and Sulfur Compounds on Kidney Health and Disease |
Sweet Potato | 📋 | | ⛔ | | 34981522 | In vitro and in vivo ameliorative effects of polyphenols from purple potato leaves on renal injury and associated inflammation induced by hyperuricemia |
Tamarind | 📋 | | ⛔ | | 36003506 | The Combination of Tamarindus indica and Coenzyme Q10 can be a Potential Therapy Preference to Attenuate Cadmium-Induced Hepatorenal Injury |
Tea Tree Essential Oil | 📋 | | ⛔ | | 32630444 | Anti-Bacterial Effects of Essential Oils Against Uropathogenic Bacteria |
Theobromine | 📋 | ✍ | ⛔ | | 37446053 | Efficacy of Theobromine and Its Metabolites in Reducing the Risk of Uric Acid Lithiasis |
Trans-Resveratrol | 📋 | | | | 29229234 | Trans-resveratrol mitigates type 1 diabetes-induced oxidative DNA damage and accumulation of advanced glycation end products in glomeruli and tubules of rat kidneys |
Vitamin B1 | 📋 | ✍ | ⛔ | | 30704890 | Vitamin B complex supplementation as a homocysteine-lowering therapy for early stage diabetic nephropathy in pediatric patients with type 1 diabetes: A randomized controlled trial |
Vitamin B2 | 📋 | ✍ | ⛔ | | 37237348 | The association of dietary intake of riboflavin and thiamine with kidney stone: a cross-sectional survey of NHANES 2007-2018 |
Vitamin B8 | 📋 | ✍ | ⛔ | | 36611810 | Myo-Inositol Supplementation Alleviates Cisplatin-Induced Acute Kidney Injury via Inhibition of Ferroptosis |
Vitamin K2 mk-4 | 📋 | ✍ | | | 14712427 | Protective Effect of Vitamins K2 and D3 on Prednisolone-Induced Loss of Bone Mineral Density in the Lumbar Spine |
Vitamin K2 mk-7 | 📋 | ✍ | | | 35139790 | Vitamin K supplementation in chronic kidney disease patients: where is the evidence? |
Watermelon | 📋 | | ⛔ | | 34841269 | Watermelon rind ethanol extract exhibits hepato-renal protection against lead induced-impaired antioxidant defenses in male Wistar rats |
Whey Protein | 📋 | ✍ | ⛔ | | 36950976 | Whey Protein Concentrate Ameliorates the Methotrexate-Induced Liver and Kidney Damage |
White Tea | 📋 | | ⛔ | | 33577915 | Ameliorative effect of white tea from 50-year-old tree of Camellia sinensis L. (Theaceae) on kidney damage in diabetic mice via SIRT1/AMPK pathway |
Wormwood Essential Oil | 📋 | | ⛔ | | 33716767 | Antioxidant and Protective Effects of Artemisia campestris Essential Oil Against Chlorpyrifos-Induced Kidney and Liver Injuries in Rats |
Yerba Mate | 📋 | ✍ | ⛔ | | 37219520 | Beneficial effects of mate-herb, Ilex paraguariensis St. Hil. against potassium dichromate-induced oxidative stress and nephrotoxicity |
Yogurt | 📋 | | ⛔ | | 36618701 | Association between probiotic, prebiotic, and yogurt consumption and chronic kidney disease: The NHANES 2010-2020 |
Yohimbine | 📋 | ✍ | | | 34265299 | Yohimbine hydrochloride inhibits benign prostatic hyperplasia by downregulating steroid 5α-reductase type 2 |
Zeaxanthin | 📋 | ✍ | ⛔ | | 28058588 | The Hypoglycemic, Hypolipidemic, and Anti-Diabetic Nephritic Activities of Zeaxanthin in Diet-Streptozotocin-Induced Diabetic Sprague Dawley Rats |